ScriptDerm Redness Relief Without Oxymetazoline
A prescription with 16 ingredients, including vitamin E and azelaic acid.
Overview
What it is
Prescription with 16 ingredients that contains azelaic acid and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens or sulfates
Fun facts
ScriptDerm is from United States. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Azelaic Acid 15%
BufferingIvermectin 1%
Metronidazole 1%
Isopropyl Palmitate
EmollientDimethicone
EmollientPluronic F127 30%
Glycerin
HumectantAloe Barbadensis Leaf Juice
Skin ConditioningC13-14 Isoparaffin
EmollientCaprylic/Capric Triglyceride
MaskingWater
Skin ConditioningLaureth-7
EmulsifyingPhenoxyethanol
PreservativePolyacrylamide
Tocopheryl Acetate
AntioxidantTriethylene Glycol
Masking
Active Ingredients:
Azelaic Acid 15%, Ivermectin 1%, Metronidazole 1%
Inactive Ingredients:
Isopropyl Palmitate, Dimethicone, Pluronic F127 30%, Glycerin, Aloe Barbadensis Leaf Juice, C13-14 Isoparaffin, Caprylic/Capric Triglyceride, Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidIvermectin is a prescription medication.
It is used to treat parasitic-worm infections, head lice, and skin conditions like rosacea.
Ivermectin is created from bacterium called Streptomyces avermitilis. We recommend speaking with a professional about using this ingredient.
Learn more about IvermectinMetronidazole is a prescription medication. It is used to treat rosacea.
We recommend speaking with a professional about this ingredient.
Isopropyl Palmitate is a texture enhancer and emollient. It is an ester of isopropyl alcohol and palmitic acid.
Palmitates are emollients. Emollients help keep your skin soft and smooth by creating a barrier that traps moisture in.
When added to cosmetics, Isopropyl Palmitate creates a silky texture and improves spreadability.
Isopropyl Palmitate may not be fungal acne safe. It can worsen acne prone skin.
Learn more about Isopropyl PalmitateDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeThis ingredient is a surfactant.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceThis ingredient is also known as "C13-14 Isoalkane".
C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.
As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.
C13-14 Isoparaffin may not be fungal-acne safe.
Learn more about C13-14 IsoparaffinThis ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglycerideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterLaureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.
This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.
Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.
It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.
We recommend speaking with a professional if you have concerns.
Learn more about PolyacrylamideTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateTriethylene Glycol is a fragrance.
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Where it's from
ScriptDerm is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated May 29, 2026 • Added by Xinran88