Glenmark Pharma Sibzeos Azelaic Acid 15%
A prescription with 9 ingredients, including azelaic acid.
Prescription with 9 ingredients that contains azelaic acid
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Key Ingredients
Benefits
Concerns
Ingredients Explained
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidBenzoic Acid is an organic acid that shows up in cosmetics as a preservative. It helps keep a product from spoiling by holding back the growth of yeast, mold, and some bacteria.
This ingredient also functions as a fragrance ingredient that helps mask the unpleasant scent of other ingredients.
The way it works is worth understanding; benzoic acid works when the formula is acidic. It is able to sneak into a microbe's cell and mess up how it functions to stop it from growing in an acidic product.
However, the acid switches to an inactive form and stops working if a product isn't acidic enough (above ~5 pH). This is why you'll often see it in low pH products or teamed up with other preservatives to cover the gap.
Safety wise, it's one of the better studied preservatives out there.
The Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe for use in cosmetic formulations at concentrations up to 5%.
A large international review found this ingredient had no effects on the human body and had low irritation potential.
Just so you know, real world use is usually much lower than the 5% ceiling (usually 1% of less).
The EU caps it at 2.5% in rinse-off products, 1.7% in oral care, and 0.5% in leave-on products.
One thing worth mentioning (it's nothing to worry about): some people get a little stinging or flushing where they apply it. This isn't a true allergy; it's a temporary and harmless reaction. This is the same kind of mild tingle you might notice from sorbic acid.
Learn more about Benzoic AcidCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerTetrasodium EDTA is the salt formed from neutralizing ethylenediamine tetraacetic acid with sodium hydroxide. It is a chelating agent and used to prevent metal ions from binding to other ingredients. This helps keep the product and ingredients stable.
Tetrasodium EDTA comes as a white solid and is soluble in water.
Isopropyl Myristate is an ester made by combining isopropyl alcohol with myristic acid.
It is primarily an emollient and penetration enhancer that gives products a lightweight, silky feel without the heaviness of oils.
This ingredient is generally considered non-toxic, non-irritating, and has low absorption potential.
You might have heard that this ingredient clogs pores. This reputation comes from the older rabbit ear studies which are more sensitive than human skin to clogging.
Dermatologist Dr. Zoe Draelos has also confirmed in a peer-reviewed paper that products containing comedogenic ingredients are not necessarily comedogenic themselves.
A small subset of people (~2%) may experience contact sensitivity so patch testing is a reasonable idea if you have reactive skin.
Since this ingredient is an ester of myristic acid (a C14 fatty acid), it falls within the carbon chain range that is known to feed Malassezia. This ingredient may not be fungal acne safe.
Learn more about Isopropyl MyristatePolysorbate 80 is a synthetic surfactant and emulsifier derived from sorbitol and oleic acid.
It reduces the surface tension between oil and water phases to help them stay mixed and stable in a formulation. In other words, it prevents your formulas from separating into an oily mess.
The CIR Expert Panel has evaluated the scientific data and found this ingredient to be safe, non-irritating, and non-sensitizing at concentrations up to 5% (it's even approved by the FDA as an OTC eye drop ingredient).
Learn more about Polysorbate 80Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideReviews
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Where it's from
Glenmark Pharma is a Indian brand
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