Overview
What it is
Prescription with 10 ingredients that contains azelaic acid
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Bayer is from Germany. This product is used in 198 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Azelaic Acid 20%
Buffering
Benzoic Acid
Masking
Cetearyl Ethylhexanoate
Emollient
Isopropyl Myristate
Emollient
Glycerin 85%
Humectant
Active Ingredients:
Azelaic Acid 20%
Inactive Ingredients:
Benzoic Acid, Cetearyl Ethylhexanoate, Isopropyl Myristate, Glycerin 85%, Propylene Glycol, Water, Stearoyl Macrogolglycerides, Glyceryl Stearate, Cetearyl Alcohol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidBenzoic Acid is an organic acid that shows up in cosmetics as a preservative. It helps keep a product from spoiling by holding back the growth of yeast, mold, and some bacteria.
This ingredient also functions as a fragrance ingredient that helps mask the unpleasant scent of other ingredients.
The way it works is worth understanding; benzoic acid works when the formula is acidic. It is able to sneak into a microbe's cell and mess up how it functions to stop it from growing in an acidic product.
However, the acid switches to an inactive form and stops working if a product isn't acidic enough (above ~5 pH). This is why you'll often see it in low pH products or teamed up with other preservatives to cover the gap.
Safety wise, it's one of the better studied preservatives out there.
The Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe for use in cosmetic formulations at concentrations up to 5%.
A large international review found this ingredient had no effects on the human body and had low irritation potential.
Just so you know, real world use is usually much lower than the 5% ceiling (usually 1% of less).
The EU caps it at 2.5% in rinse-off products, 1.7% in oral care, and 0.5% in leave-on products.
One thing worth mentioning (it's nothing to worry about): some people get a little stinging or flushing where they apply it. This isn't a true allergy; it's a temporary and harmless reaction. This is the same kind of mild tingle you might notice from sorbic acid.
Learn more about Benzoic AcidCetearyl Ethylhexanoate is derived from cetearyl alcohol and sorbic acid.
It is an emollient and helps hydrate the skin. Emollients form a barrier on the skin to prevent water from escaping.
Isopropyl Myristate is an ester made by combining isopropyl alcohol with myristic acid.
It is primarily an emollient and penetration enhancer that gives products a lightweight, silky feel without the heaviness of oils.
This ingredient is generally considered non-toxic, non-irritating, and has low absorption potential.
You might have heard that this ingredient clogs pores. This reputation comes from the older rabbit ear studies which are more sensitive than human skin to clogging.
Dermatologist Dr. Zoe Draelos has also confirmed in a peer-reviewed paper that products containing comedogenic ingredients are not necessarily comedogenic themselves.
A small subset of people (~2%) may experience contact sensitivity so patch testing is a reasonable idea if you have reactive skin.
Since this ingredient is an ester of myristic acid (a C14 fatty acid), it falls within the carbon chain range that is known to feed Malassezia. This ingredient may not be fungal acne safe.
Learn more about Isopropyl MyristateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterThis ingredient is known by its tradename Acconon C-50 EP/NF.
It is a pale-yellow, waxy solid made from a mixture of glycerol esters and polyethylene glycols (PEGs). The main function of this ingredient is to help stabilize the formulation.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholReviews
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Where it's from
Bayer is a German brand
Often compared with
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated April 28, 2025 • Added by Lapaki
