Alloy M4 Face Serum RX
A highly rated serum with 16 ingredients, including vitamin E, hyaluronic acid, and ceramides.
Overview
What it is
Serum with 16 ingredients that contains ceramides, hyaluronic acid, peptides and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
Fun facts
Alloy is from United States. This product is used in 18 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Estriol 0.3%
Palmitoyl Pentapeptide-4 0.1%
Skin ConditioningAcetyl Hexapeptide-8 0.1%
HumectantHyaluronic Acid 0.5%
HumectantCyclopentasiloxane
EmollientCaprylyl Methicone
Skin ConditioningPEG-16 Macadamia Glycerides
EmollientPolysilicone-11
PEG-12 Dimethicone/PPG-20 Crosspolymer
Ceramide AP
Skin Conditioning1,2-Hexanediol
Skin ConditioningPhosphatidylcholine
EmulsifyingJojoba Esters
EmollientIsopropyl Jojobate
EmollientJojoba Alcohol
EmollientTocopheryl Acetate
Antioxidant
Active Ingredients:
Estriol 0.3%, Palmitoyl Pentapeptide-4 0.1%, Acetyl Hexapeptide-8 0.1%, Hyaluronic Acid 0.5%
Inactive Ingredients:
Cyclopentasiloxane, Caprylyl Methicone, PEG-16 Macadamia Glycerides, Polysilicone-11, PEG-12 Dimethicone/PPG-20 Crosspolymer, Ceramide AP, 1,2-Hexanediol, Phosphatidylcholine, Jojoba Esters, Isopropyl Jojobate, Jojoba Alcohol, Tocopheryl Acetate
Key Ingredients
Benefits
Ingredients Explained
Estriol, also called oestriol, is a steroid and a weak form of estrogen. This is not an INCI ingredient and we suggest speaking with a medical professional about using this ingredient.
You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Due to its palmitic acid base, it may not be fungal acne safe.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itās often referred to as a āBotox-likeā ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itās not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnāt a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidCyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneCaprylyl Methicone is a synthetic and lightweight silicone fluid. It gives products a silky, dry-touch finish without the heaviness of pure oils.
Though the EU CosIng Database lists this ingredient as a skin conditioner, it is also used for sensory reasons. It spreads easily, cuts greasiness, and reduces tackiness.
This ingredient is volatile which means it will mostly evaporate (but it evaporates slower than older cyclomethicones, like Cyclotetrasiloxane).
Typical concentration ranges from 1-30% depending on if it's being used to tweak the feel of a product or acting as the main emollient.
Learn more about Caprylyl MethiconePEG-16 Macadamia Glycerides isn't fungal acne safe.
Polysilicone-11 is a film-forming silicone that creates a non-tacky and matte finish on the skin. It's commonly used to improve texture, absorb excess oil, and help active ingredients spread evenly.
Due to its "rubber-like" structure, it stays on the skin's surface instead of being absorbed. On the skin, it creates a flexible layer that enhances wearability and stability.
PEG-12 Dimethicone/PPG-20 Crosspolymer is a type of silicone.
Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Learn more about Ceramide AP1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Ā
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesĀ
Phosphatidylcholine (PC) is a type of phospholipid, a class of molecule that makes up our own cell membranes.
It has a glycerol backbone, two fatty acid tails (mostly linoleic, palmitic, and oleic), and a phosphate-choline head group.
In skincare, PC pulls double duty:
The linoleic acid it carries gets incorporated into skin ceramides and helps reinforce the lipid matrix.
Interestingly, it can help top of the omega-6 fatty acid that's often low in acne-prone and atopic skin. There's a sizeable body of literature that supports its use in dry, barrier-impaired, and breakout-prone skin.
There are two kinds of PC you'll see on ingredient lists.
Use levels range from <1% as a liposomal carrier and between 20-40% in lamellar matrix sytems.
Learn more about PhosphatidylcholineJojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.
This ingredient has high oxidative stability, meaning it doesn't break down when exposed to oxygen.
Its similarity to our skin's natural oils makes it a great emollient. Emollients help soften and soothe our skin by creating a barrier on top. This barrier helps trap moisture in, keeping skin hydrated.
It is created using either the hydrogenation or transesterification processes on jojoba oil.
Learn more about Jojoba EstersWe don't have a description for Isopropyl Jojobate yet.
Jojoba Alcohol is a fatty alcohol.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateReviews
Where it's from
Alloy is a American brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usĀ· Updated September 15, 2025 • Added by amydavis4