What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Estriol 0.3%
Palmitoyl Pentapeptide-4 0.1%
Skin Conditioning
Acetyl Hexapeptide-8 0.1%
Humectant
Hyaluronic Acid 0.5%
Humectant
Cyclopentasiloxane
Emollient
Caprylyl Methicone
Skin Conditioning
PEG-16 Macadamia Glycerides
Emollient
Polysilicone-11
PEG-12 Dimethicone/PPG-20 Crosspolymer
Ceramide AP
Skin Conditioning
1,2-Hexanediol
Skin Conditioning
Phosphatidylcholine
EmulsifyingJojoba Esters
Emollient
Isopropyl Jojobate
EmollientJojoba Alcohol
Emollient
Tocopheryl Acetate
Antioxidant
Estriol 0.3%, Palmitoyl Pentapeptide-4 0.1%, Acetyl Hexapeptide-8 0.1%, Hyaluronic Acid 0.5%, Cyclopentasiloxane, Caprylyl Methicone, PEG-16 Macadamia Glycerides, Polysilicone-11, PEG-12 Dimethicone/PPG-20 Crosspolymer, Ceramide AP, 1,2-Hexanediol, Phosphatidylcholine, Jojoba Esters, Isopropyl Jojobate, Jojoba Alcohol, Tocopheryl Acetate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itâs often referred to as a âBotox-likeâ ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itâs not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnât a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidYou might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4
