Avène Cleanance Comedomed Concentrate Blemish Control Serum Versus Avène Comedomed+ Soin Intensif Anti-Imperfections
Updated on September 17, 2025
Overview
What they are
These products are both reef safe serums. They have a total of 10 ingredients in common
Cool Features
They both contain exfoliants
Suited For
They're both likely to be good for dry skin, brightening skin and scar healing
Free From
They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates
What's Inside
They both contain harsh alcohols
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Avène Cleanance Comedomed Concentrate Blemish Control Serum 10 ingredients
Avène Comedomed+ Soin Intensif Anti-Imperfections 11 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Avène Cleanance Comedomed Concentrate Blemish Control Serum 10 ingredients
Avène Comedomed+ Soin Intensif Anti-Imperfections 11 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinIsopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.
This ingredient is an astringent alcohol. Astringent alcohols may also irritate skin as they high amounts may strip away your skin's natural oils.
Other types of astringent alcohols include:
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.
Learn more about Isopropyl AlcoholWe don't have a description for PEG-6 yet.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.
Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers
Learn more about Polyacrylate-13Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobutenePolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
The unique structure of silica enhances the spreadability and smoothness of textures. It also works as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
We don't have a description for Silybum Marianum Fruit Extract yet.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.
Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.
Learn more about Sorbitan IsostearateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Avène Cleanance Comedomed Concentrate Blemish Control Serum 10 ingredients
Avène Comedomed+ Soin Intensif Anti-Imperfections 11 ingredients

Reviews
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Avène Cleanance Comedomed Concentrate Blemish Control Serum 10 ingredients
Avène Comedomed+ Soin Intensif Anti-Imperfections 11 ingredients
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