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Updated on July 18, 2023

Overview

What they are

These products are both reef safe . They have a total of 12 ingredients in common

Cool Features

They both contain hyaluronic acid and peptides

Suited For

They're both likely to be good for dry skin and brightening skin

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

ma:nyo Bifida Biome Complex Ampoule
ma:nyo Bifida Biome Complex Ampoule
Ampoule
South Korean Brand South Korea

Ingredient Info

Click any item below to learn more and see relevant ingredients
ph level
7.4

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Bifida Biome Complex Ampoule
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Bifida Ferment Filtrate Skin Conditioning

We don't have a description for Bifida Ferment Filtrate.

Lactobacillus Ferment Lysate Skin Conditioning

We don't have a description for Lactobacillus Ferment Lysate.

Lactococcus Ferment Lysate Skin Conditioning

We don't have a description for Lactococcus Ferment Lysate.

Saccharomyces Ferment Filtrate Humectant

Saccharomyces Ferment Filtrate is created from fermenting Saccharomyces, a yeast also known as baker's yeast or brewer's yeast.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Niacinamide Smoothing
Niacinamide  •  6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Lactobacillus/Pumpkin Fruit Ferment Filtrate Skin Conditioning

We don't have a description for Lactobacillus/Pumpkin Fruit Ferment Filtrate.

Aureobasidium Pullulans Ferment Skin Conditioning

We don't have a description for Aureobasidium Pullulans Ferment.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid  •  4 Benefits  •  May cause irritation

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Sodium Hyaluronate Crosspolymer Humectant, Skin Conditioning
Hyaluronic Acid

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hydrolyzed Sodium Hyaluronate Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

Potassium Hyaluronate Skin Conditioning

We don't have a description for Potassium Hyaluronate.

Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Hydroxypropyltrimonium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

Leontopodium Alpinum Callus Culture Extract Antioxidant, Humectant, Skin Protecting
Antioxidant

Leontopodium Alpinum Callus Culture Extract is an antioxidant.

Cutibacterium Granulosum Ferment Extract Filtrate Emollient, Skin Conditioning

We don't have a description for Cutibacterium Granulosum Ferment Extract Filtrate.

Unknown Full details ->
Asiaticoside Antioxidant, Skin Conditioning
Antioxidant

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Asiatic Acid Skin Conditioning, Stabilising

Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.

Madecassic Acid Skin Conditioning

Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.

Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Squalane Emollient, Skin Conditioning
1 / 0
Helps hydrate Dry Skin

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Copper Tripeptide-1 Skin Conditioning
Peptide  •  Helps with Anti-Aging

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Dextrin Absorbent

Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Benzyl Glycol Solvent

We don't have a description for Benzyl Glycol.

Sodium Phytate

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Hydrolyzed Algin

We don't have a description for Hydrolyzed Algin.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Epigallocatechin Gallate Antioxidant
Antioxidant

EGCG is most famous for being found in green tea. It is a type of catechin, a potent antioxidant.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Physalis Alkekengi Calyx Extract Skin Conditioning

We don't have a description for Physalis Alkekengi Calyx Extract.

Unknown Full details ->
Hydrolyzed Glycosaminoglycans Humectant, Skin Conditioning

We don't have a description for Hydrolyzed Glycosaminoglycans.

Polyglyceryl-10 Laurate Skin Conditioning
Not safe for Fungal Acne

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Very Disliked Full details ->
Theobroma Cacao Seed Extract Antioxidant
Antioxidant

Theobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.

Advanced Night Repair Synchronized Multi-Recovery Complex Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Peg-8 Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

Very Disliked Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Bis-Peg-18 Methyl Ether Dimethyl Silane Emollient, Humectant, Skin Conditioning

Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.

Disliked Full details ->
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Glycereth-26 Humectant
0 / 0

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

0 Com. / 0 Irr.
Peg-75 Humectant, Solvent

We don't have a description for Peg-75.

Unknown Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Adansonia Digitata Seed Extract Skin Conditioning

We don't have a description for Adansonia Digitata Seed Extract.

Tripeptide-32 Skin Conditioning
Peptide

Tripeptide-32 is made up of amino acids proline, serine, and threonine. Amino acids are used by the skin to create proteins and a healthy skin barrier.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Yeast Extract Skin Conditioning, Skin Protecting

We don't have a description for Yeast Extract.

Lactobacillus Ferment Skin Conditioning

Lactobacillus Ferment is created by fermenting the Lactobacillus bacteria. It helps keep our skin's natural barrier and microbiome healthy.

Cola Acuminata Seed Extract Skin Conditioning

We don't have a description for Cola Acuminata Seed Extract.

Unknown Full details ->
Anthemis Nobilis Flower Extract Masking, Perfuming, Skin Conditioning
Fragrance

Anthemis Nobilis Flower Extract is from the Roman Chamomile flower.

Hydrolyzed Algin

We don't have a description for Hydrolyzed Algin.

Pantethine Emollient

We don't have a description for Pantethine.

Unknown Full details ->
Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Sodium Rna Skin Conditioning

We don't have a description for Sodium Rna.

Unknown Full details ->
Bisabolol Masking, Skin Conditioning, Soothing
Helps reduce irritation

Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.

Squalane Emollient, Skin Conditioning
1 / 0
Helps hydrate Dry Skin

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Oleth-3 Phosphate
2 / 2

Oleth-3 Phosphate is created from phosphoric acid and Oleth-3.

2 Com. / 2 Irr.
Unknown Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Oleth-3 Emulsifying
5 / 2

Oleth-3 comes from oleyl alcohol. It is an emulsifier that helps reduce surface tension of dirt and pollutants to be washed away.

5 Com. / 2 Irr.
Unknown Full details ->
Oleth-5 Emulsifying
3 / 0

Oleth-5 comes from oleyl alcohol. It is an emulsifier that helps reduce surface tension of dirt and pollutants to be washed away.

3 Com. / 0 Irr.
Unknown Full details ->
Choleth-24 Emulsifying
0 / 0

Choleth-24 comes from the cholesterol of lanolins. It is used as an emulsifier, or to help stabilize other ingredients.

0 Com. / 0 Irr.
Unknown Full details ->
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Jojoba Wax Peg-120 Esters
Not safe for Fungal Acne

Jojoba Wax Peg-120 Esters isn't fungal acne safe.

Disliked Full details ->
Ceteth-24 Cleansing, Emulsifying

We don't have a description for Ceteth-24.

Unknown Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0
Vitamin E  •  Antioxidant  •  Helps brighten skin

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
Tetrasodium EDTA

Tetrasodium EDTA is the salt formed from neutralizing ethylenediamine tetraacetic acid with sodium hydroxide. It is a chelating agent and used to prevent metal ions from binding to other ingredients. This helps keep the product and ingredients stable.

Disliked Full details ->
BHA Antioxidant, Masking
Antioxidant

This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Potassium Sorbate Preservative
Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
CI 14700 Cosmetic Colorant
2 / 1

Ci 14700 is a synthetic red dye.

2 Com. / 1 Irr.
Unknown Full details ->
Yellow 11 Cosmetic Colorant

We don't have a description for Yellow 11.

Unknown Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Liked

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Emollient, Skin Conditioning
Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Emulsifying, Skin Conditioning
Liked

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Hydrogenated Lecithin is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within.

The phospholipids in Hydrogenated Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier to be better absorbed.

As an emulsifier, it prevents oil and water ingredients from separating.

Learn more about Hydrogenated Lecithin
Solvent
Liked

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Propanediol is not likely to cause sensitivity and considered safe to use.

It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning
Loved

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Caffeine is an antioxidants, which help with the signs of aging. This is because antioxidants help fight skin-damaging free radical molecules.

While caffeine is used to treat cellulite and and dark circles, further studies are needed to prove this. It has been believed to help with these skin conditions due to its ability to dilate blood vessels and increase blood flow.

Some studies are looking into caffeine's ability to protect against UV rays.

Learn more about Caffeine

We don't have a description for Hydrolyzed Algin.

Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Bifida Biome Complex Ampoule
33
7
3
2
liked
mixed
disliked
not rated
Advanced Night Repair Synchronized Multi-Recovery Complex Serum
16
5
11
11
liked
mixed
disliked
not rated

When to use

161 Routines
42% use in am
58% use in pm
91% use every day
When to use See routines that use it ->
277 Routines
17% use in am
82% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

ma:nyo Bifida Biome Complex Ampoule 45 ingredients

4.7 /5
from 3 ratings
Absorbs Well (1) Hydrating (1) No Scent (1) Works Well (1)
traceyy's avatar

traceyy

27 days ago · Combination Skin
Review

WRP! I loved this serum. It was hydrating and sunk in well to my skin. My skin felt more plump and supple.

Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum 43 ingredients

4.6 /5
from 5 ratings
Expensive (2) Hydrating (1) Light Scent (1) Sticky (1) Works Well (1)
NSmith's avatar

NSmith

4 months ago · Combination Skin
Review

Received a sample with purchase at Ulta. The serum feels nice, but ultimately is not worth the money. There are other products that can do the same...

Received a sample with purchase at Ulta. The serum feels nice, but ultimately is not worth the money. There are other products that can do the same for less.

rodney's avatar

rodney

1 month ago · Dry Skin
Review

helps so much with dryness from tretinoin + very hydrating