up&up Maximum Strength Hydrocortisone 1% Anti-Itch Cream
A highly rated body treatment with 16 ingredients.
Overview
What it is
Body treatment with 16 ingredients
Suited For
It has ingredients that are good for dry skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances or silicones
Fun facts
up&up is from United States. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Hydrocortisone 1%
Aloe Barbadensis Leaf Juice
Skin ConditioningAluminum Sulfate
AstringentBeeswax
Emulsion StabilisingCalcium Acetate
MaskingCetearyl Alcohol
EmollientDextrin
AbsorbentGlycerin
HumectantMaltodextrin
AbsorbentMethylparaben
PreservativeParaffinum Liquidum
EmollientPetrolatum
EmollientPropylparaben
PreservativeSodium Cetearyl Sulfate
CleansingSodium Lauryl Sulfate
CleansingWater
Skin Conditioning
Active Ingredients:
Hydrocortisone 1%
Inactive Ingredients:
Aloe Barbadensis Leaf Juice, Aluminum Sulfate, Beeswax, Calcium Acetate, Cetearyl Alcohol, Dextrin, Glycerin, Maltodextrin, Methylparaben, Paraffinum Liquidum, Petrolatum, Propylparaben, Sodium Cetearyl Sulfate, Sodium Lauryl Sulfate, Water
Benefits
Concerns
Ingredients Explained
Hydrocortisone is the name for the hormone cortisol when used in medication.
It is medication and not technically a cosmetic ingredient. Most countries allow topical creams to contain up between 0.05 - 2.5% (depending on the country) of hydrocortisone without a prescription. Higher amounts usually require a prescription from a professional.
Hydrocortisone can help relieve rashes, eczema, itching, and other inflammation induced skin conditions.
We recommend speaking with a professional about using this ingredient.
Learn more about HydrocortisoneAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceAluminum Sulfate is a type of sulfate.
Beeswax is natural wax produced by honey bees to build their honeycomb.
Because it forms a protective layer on your skin, it can help lock in moisture and reduce water loss. It is also widely used as a thickener and emulsifier in lip balms and lotions. Research suggests beeswax containing moisturizers can support skin barrier integrity.
In comedogenic testing, Beeswax scored a 0-2, which is on the low end. Whether or not a product clogs your pores really comes down to the formula as a whole (not any single ingredient on its own).
Cera Alba is the white, bleached form of this ingredient.
Just so you know, beeswax is not vegan since it is animal-derived. It cannot be removed with water, but can be taken off with an oil cleanser.
People with a known Propolis allergy also report to have reactions from beeswax.
Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1). Both of these fall within the C11-C24 feeding window.
The Malassezia yeast can potentially cleave these esters and release usable fatty acids, so this ingredient may not be fungal acne safe. However, not everyone will react to this ingredient.
Learn more about BeeswaxWe don't have a description for Calcium Acetate yet.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholDextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMaltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
In food, Maltodextrin is used to improve the texture and thicken a product. Due to its structure, it can help create a gel texture. As an emulsion stabilizer, it helps keep the ingredients in a product together.
As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.
Maltodextrin is water soluble and has a sweet taste.
Learn more about MaltodextrinMethylparaben is a synthetic preservative and one of the most widely used in the world. It has a simple, but important job: prevent your products from going bad by stopping bacteria, yeast, and mold from growing.
Typical use levels are low, often 0.1-0.3%.
This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.
In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.
Here's the science behind the noise behind parabens/hormones as well:
Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.
You get a stronger estrogenic effect from eating tofu, actually.
It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.
There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.
But as it stands today, this ingredient is considered safe at permitted levels.
Learn more about MethylparabenParaffinum Liquidum is a highly-refined cosmetic-grade mineral oil. It is also known as liquid paraffin.
Despite its controversial reputation, the science is pretty clear: it's one of the most well-studied and effective moisturizing ingredients out there.
As an occlusive, it forms a protective layer on the skin that locks in moisture and prevents transepidermal water loss (TEWL). This makes it especially great for compromised skin barriers.
The "it clogs your pores" myth has been around for decades; a study found that industrial-grade mineral oil may be comedogenic but cosmetic-grade mineral oil is not (these two are very, very different).
A 2017 review concluded that cosmetic use of mineral oils and waxes does not present a risk to consumers due to absorption.
Mineral oil got a bad rap from the old rabbit ear studies. When tested on actual human skin, cosmetic-grade mineral oil showed no comedogenic activity. The rating of 0 is a correction of outdated science.
Mineral oil is an inert substance with no fatty acids so there's nothing to feed Malassezia. This ingredient is fungal acne safe.
Learn more about Paraffinum LiquidumPetrolatum is more commonly known as petroleum jelly. It is created by mixing waxes and mineral oils.
This ingredient is effective at reducing water loss by 99%. This is because it is an occlusive. Occlusives create a hydrophobic barrier on the skin to prevent evaporation. This property makes it great for hydrating dry skin.
Pro tip: Use occlusives, such as this ingredient, on damp skin for the best results.
The quality or origin of petrolatum is only known when disclosed by the brand. Most cosmetic petrolatum has gone through several purification stages.
Another benefit of occlusives is it protects your skin against infection or allergies.
Petrolatum is fungal acne safe. It is a hydrocarbon with no fatty acid structure, so Malassezia cannot metabolize it. In-vitro studies support negligible growth stimulation as well.
It's also worth noting that petrolatum has a comedogenic rating of 0. In updated rabbit ear testing (and in human testing), petrolatum was found to be not comedogenic. This means it didn’t promote comedone formation in standard models.
Learn more about PetrolatumPropylparaben is a preservative and one of the most widely used members of the paraben family (it's been used in cosmetics for over a century now).
It works by disrupting microbial cell membranes and enzymes, and is a broad-spectrum protector that works exceptionally well against molds, yeasts, and gram-positive bacteria.
You'll likely see it paired with methylparaben to cover the full range (including gram-negative bacteria).
This ingredient is effective at low concentrations (~0.2-0.5%) and stable across a wide pH range (4.5-7.5 pH). It's effectiveness drops off above pH 8 and it can lose potency when combined with non-ionic surfactants like polysorbate 80 due to micellization.
The regulatory bodies have concluded this ingredient to be safe as used in cosmetics. The EU has capped it at 0.14% and combined parabens are not to exceed 0.8%.
While parabens do cross the stratum corneum, only about 1% remains for absorption into the body. This is because most of it is metabolized within living skin.
Learn more about PropylparabenSodium Cetearyl Sulfate is a type of sulfate.
Sodium Lauryl Sulfate (SLS) is a surfactant, cleansing agent, and foaming agent. You'll find it in a wide range of products from shampoos to face cleansers.
It:
The Cosmetic Ingredient Review Panel has assessed it in 1983, 2002, and 2005 and found it to be safe in formulations at low concentrations.
SLS is a well-documented skin irritant at higher concentrations or with prolonged exposure. It's actually the gold standard positive control used in dermatological patch testing, meaning doctors use it because they know it will cause a reaction in people.
In one large study of 43,000 patiences tested with 0.25% SLS, about 22% showed some level of reactivity. It increases transepidermal water loss that disrupts your outermost layer of skin.
Face cleansers often pair this ingredient with mild co-surfactants like Cocamidopropyl Betaine to buffer its harshness.
Just so you know, SLS does not trigger true allergic contact dermatitis. This just means it can irritate your skin but doesn't cause your immune system to develop a lasting allergy to it.
Despite internet rumors, SLS is not considered a carcinogen by any major regulatory body.
Learn more about Sodium Lauryl SulfateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
up&up is a American brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated May 31, 2025 • Added by anemone