Transparent Lab Oil Based Cleanser

It is also an emollient and helps condition the skin.

This ingredient is very interesting as a hydrator; most moisturizers are either occlusives, humectants, or emollients. Isostearyl isostearate works through another route named "internal occlusion" by the head researcher.

Isostearyl isostearate nudges the skin's own lipids into a denser, more tightly packed arrangement. Packing the deeper layers of the stratum corneum together more efficiently means less water is able to escape.

This is a barrier-improving mechanism that hadn't been described before and plastic occlusion stress tests confirmed it improved the skin's water-permeability barrier function

Just one thing worth noting from the same review: this ingredient increased the penetration rate of a test drug through excised human skin. Though this ingredient is not classified as a penetration enhancer, it does interact with the barrier rather than sitting totally inert on top.

Fungal acne:
The Malassezia yeast feeds on fatty acids and esters in the C11-24 range. Since both halves of this molecules are C18, it may not be fungal acne safe.

While this ingredient was given a comedogenic rating of 4-5, research has shown that finished products containing comedogenic ingredients don't always increase the formation of microcomedones.

Since isostearic acid is a C18 fatty acid, this ingredient falls within the range that Malassezia feeds on. This ingredient may not be fungal acne safe.

This ingredient has been found safe for use in cosmetics and broader PEG family testing shows minimal irritation/sensitization. The molecule's large size also means it isn't expected to penetrate skin to any meaningful degree.

Fungal acne note: This ingredient may not be fungal acne safe due to isostearic acid (C18). Isostearic acid falls into the C11-24 range that Malassezia can feed on.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.