TDF Derma Formula Non Drying Cleansing Lotion

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

The Cosmetic Ingredient Review Panel has assessed it in 1983, 2002, and 2005 and found it to be safe in formulations at low concentrations.

SLS is a well-documented skin irritant at higher concentrations or with prolonged exposure. It's actually the gold standard positive control used in dermatological patch testing, meaning doctors use it because they know it will cause a reaction in people.

In one large study of 43,000 patiences tested with 0.25% SLS, about 22% showed some level of reactivity. It increases transepidermal water loss that disrupts your outermost layer of skin.

Face cleansers often pair this ingredient with mild co-surfactants like Cocamidopropyl Betaine to buffer its harshness.

Just so you know, SLS does not trigger true allergic contact dermatitis. This just means it can irritate your skin but doesn't cause your immune system to develop a lasting allergy to it.

Despite internet rumors, SLS is not considered a carcinogen by any major regulatory body.

Some people who are allergic to imidazolidinyl urea also react to diazolidinyl urea. It ranked as the 14th most common allergen in patch tests from 2005–06.

Safety reviews show that at concentrations under 0.5%, the formaldehyde released remains below the accepted safety limit, making it considered safe for cosmetic use.

Ultimately, its safety depends on individual skin sensitivity and personal comfort with formaldehyde-releasing preservatives.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.

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This ingredient is safe in cosmetics when formulated to be non-sensitizing and concentrations must not exceed 7.5 ppm in leave-on products / 15 ppm in rinse-off products.

Unfortunately, this ingredient has a well-documented sensitization story. Studies spanning several decades have shown this ingredient + MI to cause skin irritation and allergies.

The use of this ingredient varies around the world:

This just means this ingredient is most likely non-sensitizing in rinse-off products unless you've been diagnosed with a contact allergy to isothiazolinones.

Since then, numerous studies have shown this ingredient to cause contact dermatitis, or skin irritation.

The use of this ingredient varies around the world: