Lira Clinical Bio Enzyme Cleanser
A highly rated face cleanser with 13 ingredients, including vitamin E.
This mild gel cleanser is mild enough to cleanse without leaving skin feeling tight or stripped.
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What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantCocamidopropyl Hydroxysultaine
CleansingTriethanolamine
BufferingVitis Vinifera Seed Extract
AntimicrobialCarica Papaya Fruit Extract
Skin ConditioningAnanas Sativus Fruit Extract
Skin ConditioningLeontopodium Alpinum Meristem Cell Culture
Skin ConditioningPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningTocopheryl Acetate
AntioxidantAloe Barbadensis Leaf Juice Powder
Skin ConditioningXanthan Gum
EmulsifyingWater, Glycerin, Cocamidopropyl Hydroxysultaine, Triethanolamine, Vitis Vinifera Seed Extract, Carica Papaya Fruit Extract, Ananas Sativus Fruit Extract, Leontopodium Alpinum Meristem Cell Culture, Phenoxyethanol, Ethylhexylglycerin, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice Powder, Xanthan Gum
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCocamidopropyl Hydroxysultaine is a synthetic cleansing agent, though it is derived from coconut oil.
It is used to enhance the texture of products by boosting lather and thickening the texture. As a cleanser, Cocamidopropyl Hydroxysultaine is mild.
Triethanolamine (TEA) is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.
PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.
If you are looking for the tea leaf ingredient, click here.
Learn more about TriethanolamineVitis Vinifera Seed Extract comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.
The components of grape seeds have many skin benefits. Research has found it to be antimicrobial and anti-inflammatory. It also contains many potent antioxidants such as Vitamin E , Vitamin C, proanthocyanidins, polyphenols, flavonoids, and anthocyanins. Proanthocyanidin has been shown to help even out skin tone.
Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.
The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.
Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.
Learn more about Vitis Vinifera Seed ExtractCarica Papaya Fruit Extract comes from the flesh of the papaya. It's a skin conditioning agent that carries a mix of bioactives like papain, beta-carotene, and vitamin C.
These bioactive compounds give it two main talking points:
1. Papain is a proteolytic enzyme that provides mild exfoliation, helping skin look smoother and more even.
2. The carotenoids and vitamin C provide some antioxidant activity.
It's pretty compatible with most ingredients, but just sure to space out enzyme products with strong acids/retinoids to avoid over-doing it.
Maximum reported concentration is around 0.1% and most leave-on products use just 0.05%. If you see higher figures like 5-10%, this is usually the pre-diluted material from raw extract suppliers.
This ingredient has an assuring safety record and there's a lack of clinical case reports of dermatitis from using it.
The only caveat is allergy: patch test if you have a papaya or latex-fruit allergy.
Learn more about Carica Papaya Fruit ExtractThis extract comes from the pineapple fruit. Its main claim to fame is bromelain, a gentle exfoliator that helps remove dead skin cells from the outermost layer of skin.
Exfoliation from bromelain is considered a gentler alternative to physical or chemical exfoliants; this makes it suitable for sensitive skin types.
Beyond exfoliation, this extract also contains natural sugars with humectant properties and some vitamin C.
Overall, this is a well-tolerated and low-risk ingredient unless you have a pineapple allergy.
Learn more about Ananas Sativus Fruit ExtractWe don't have a description for Leontopodium Alpinum Meristem Cell Culture yet.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateAloe Barbadensis Leaf Juice Powder comes from the aloe plant.
You may know Aloe to be a good sunburn reliever and inflammation reducer. This is because it contains many components that are known to help reduce irritation and itchiness.
Aloe leaves are also great moisturizers. They are naturally rich in polysaccharides, a carbohydrate made of sugars. Polysaccharides are able to mimic the carbs found in the top layer of your skin. This can help keep your skin hydrated.
Aloe contains the antioxidants Vitamins A, C, and E. These vitamins neutralize free radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe does not protect against UV rays, despite it soothing sunburns.
Learn more about Aloe Barbadensis Leaf Juice PowderXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumReviews
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Where it's from
Lira Clinical is a American brand
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Read more about us· Updated February 3, 2026 • Added by libbyjoyner