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Updated on May 16, 2024

Overview

What they are

These products are both fungal acne (malassezia) safe facial treatments. They have a total of 4 ingredients in common

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

up&up Maximum Strength 10% Benzoyl Peroxide Gel Acne Medication
Differin Adapalene Gel 0.1% Acne Treatment
Differin Adapalene Gel 0.1% Acne Treatment
Facial Treatment
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Maximum Strength 10% Benzoyl Peroxide Gel Acne Medication
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Hydroxypropyl Methylcellulose Emulsion Stabilising

This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.

Unknown Full details ->
Laureth-4 Emulsifying, Masking
5 / 4 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

5 Com. / 4 Irr.
Unknown Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Adapalene Gel 0.1% Acne Treatment
Adapalene
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 2 Benefits 2 Concerns

Adapalene is a type of retinoid and common acne treatment.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Poloxamer 182 Emulsifying

We don't have a description for Poloxamer 182.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Buffering
Mixed

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Maximum Strength 10% Benzoyl Peroxide Gel Acne Medication
1
1
2
2
liked
mixed
disliked
not rated
Adapalene Gel 0.1% Acne Treatment
2
1
4
1
liked
mixed
disliked
not rated

When to use

92 Routines
43% use in am
57% use in pm
85% use every day
When to use See routines that use it ->
1,807 Routines
8% use in am
92% use in pm
75% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.8 /5
from 17 ratings
Absorbs Well (4) Works Well (3) Light (3)
BrittBrine's avatar

BrittBrine

7 months ago · Sensitive Skin
Review

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest...

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest time. My skin looks and feels so much better and I've only been using it for about 2-3 months now.

jojoswrld_'s avatar

jojoswrld_

6 months ago · Dry Skin
Review

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin,...

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin, but it clears over time and leaves the skin incredibly firm and smooth. It’s the only not cruelty-free product I use just because it’s benefitted me so greatly and, in my opinion, is indisputably the best prescription-grade retinoid especially for sensitive skin.