Versus

Menarini Tretinoin Gel 0.05% Versus La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne

Prescription
Facial Treatment
Italian Brand Italy
French Brand France

Updated on April 16, 2025

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates

What's Inside

They both contain parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Preservative

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

Methylparaben can be synthetically created. It can also be found naturally in some fruits, such as blueberries.

Oftentimes, Methylparaben is combined with other parabens to help increase the shelf life.

The safety of Methylparaben is currently being studied. While ongoing studies are looking into the safety of parabens, the results have been very mixed. Some studies have not found Methylparaben to be harmful.

Learn more about Methylparaben
Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

241 Routines
1% use in am
99% use in pm
69% use every day
When to use See routines that use it ->
397 Routines
5% use in am
95% use in pm
67% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Menarini Tretinoin Gel 0.05% 11 ingredients

5.0 /5
from 3 ratings
Drying (1) Great Value (1) Works Well (1)
SailorMoon_954's avatar

SailorMoon_954

1 year ago
Review

help with my acne but drying

m51's avatar

m

19 days ago
Review

It is amazing for acne. I had forehead acne where it was cysts, comedies, fungal acne. It went all away using this. I had deep rooted scarring and hyperpigmentation marks and scars and this helped heal it all. Problem is you can burn yourself if you don’t use it sparingly, in a consistent routine. It also is very very drying so you need to moisture a lot. It also causes ur skin to flake as this Show more

#great value
#drying
#works well

La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne 8 ingredients

4.5 /5
from 6 ratings
Drying (1) Irritating (1) No Scent (1)
Petrichoria's avatar

Petrichoria

2 years ago
Review

Tremendously helped me control my acne due to PCOS and is fungal-acne safe. It caused a bit of a purge in the first few weeks as my skin acclimated, but it definitely calmed any active acne down, as well controlled my oily skin. 100/10.