Dermaceutic Laboratoire Panthenol Ceutic Nourishing Restoring Ointment Versus Glenmark Pharma Tacrolimus Ointment 0.03%
This barrier-repair treatment is formulated around Panthenol and Butyrospermum Parkii Butter to strengthen the skin barrier and hydrate skin.
This hydrating prescription is formulated around Petrolatum and Cera Alba to hydrate skin.
What's inside
What's inside
Key Ingredients
No key ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cera alba is beeswax, or the wax used by bees to make honeycombs. It is a texture-enhancer and emollient. A study from 2003 found beeswax to be a stronger emollient than ingredients such as petroleum jelly.
As an emollient, beeswax helps hydrate the skin by creating a barrier on top. This barrier traps moisture in.
Emulsifiers help prevent ingredients from separating. This helps create consistent texture.
The structure of beeswax is mainly long-chain alcohols and the esters of fatty acids.
There are three types of beeswax: yellow, white, and absolute. Yellow is pure beeswax taken from the honeycomb. White beeswax is created by filtering or bleaching yellow beeswax. Absolute beeswax is created by treating beeswax with alcohol. Beeswax used in cosmetics are purified.
Beeswax has been used throughout history and even in prehistoric times. Some common uses for beeswax still used today are making candles, as a waterproofing agent, and polish for leather.
Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1). Both of these fall within the C11-C24 feeding window.
The Malassezia yeast can potentially cleave these esters and release usable fatty acids, so this ingredient may not be fungal acne safe. However, not everyone will react to this ingredient.
Learn more about Cera AlbaParaffin is a solid wax that pulls its weight as an emollient, occlusive, and consistency-booster.
It softens skin and lays down a protective film to slow water loss and gives products a stable body and structure.
The cosmetic grade stuff is highly refined with a solid safety record. The CIR Expert Panel has repeatedly reaffirmed this ingredient to be safe in current practices of use and concentration.
The worry about carcinogenic compounds only applies to industrial grades, not the purified version used in skincare.
Despite its reputation, the highly reformed form is non-comedogenic and doesn't penetrate deeply into skin.
The good news for fungal-acne prone folks: the Malassezia yeast feeds on fatty acids and lipids and paraffin doesn't contain any of these (so there's nothing for the yeast to metabolize). This ingredient is considered fungal acne safe.
Learn more about ParaffinParaffinum Liquidum is a highly-refined cosmetic-grade mineral oil. It is also known as liquid paraffin.
Despite its controversial reputation, the science is pretty clear: it's one of the most well-studied and effective moisturizing ingredients out there.
As an occlusive, it forms a protective layer on the skin that locks in moisture and prevents transepidermal water loss (TEWL). This makes it especially great for compromised skin barriers.
The "it clogs your pores" myth has been around for decades; a study found that industrial-grade mineral oil may be comedogenic but cosmetic-grade mineral oil is not (these two are very, very different).
A 2017 review concluded that cosmetic use of mineral oils and waxes does not present a risk to consumers due to absorption.
Mineral oil got a bad rap from the old rabbit ear studies. When tested on actual human skin, cosmetic-grade mineral oil showed no comedogenic activity. The rating of 0 is a correction of outdated science.
Mineral oil is an inert substance with no fatty acids so there's nothing to feed Malassezia. This ingredient is fungal acne safe.
Learn more about Paraffinum Liquidum
