Zymogen Dr. White The First Serum

Zymogen Dr. White The First Serum

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Overview

What it is

Serum with 11 ingredients that contains arbutin

Cool Features

It is vegan and reef safe

Suited For

It has ingredients that are good for dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Zymogen is from Singapore.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Key Ingredients

Benefits

Ingredients Explained

Aspergillus/Saccharomyces/Rice Ferment Filtrate isn't fungal acne safe.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Antioxidant, Bleaching, Skin Conditioning

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

This ingredient has the ability to block tyrosinase, an enzyme that starts the process of skin darkening. When applied to the skin, arbutin works at a slow pace. This can make it less irritating than similar ingredients.

Kojic Acid is a similar ingredient.

Learn more about Arbutin

We don't have a description for PEG/PPG-18/4 Copolymer yet.

Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

This ingredient is a filtrate from soymilk that has been fermented with Lactobacillus. The word "filtrate" means you're getting fermentation by-products, not live probiotic bacteria.

It is a gentle skin conditioning ingredient used to help skin feel softer, calmer, and more hydrated. In cosmetic research, "probiotic/postbiotic" style ingredients are commonly discussed in the context of supporting the skin's micro-ecology and barrier function.

Just be cautious if you're allergic to soy, and be sure to patch test even though it's processed/filtered.

Learn more about Lactobacillus/Soymilk Ferment Filtrate
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning, Skin Protecting, Soothing

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Learn more about Allantoin
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water

This ingredient comes from the safflower plant. It has skin conditioning properties and offers antioxidant support.

Most research for this ingredient is preclinical, meaning its done on cell cultures or animal models. These studies suggest compounds found in safflower can reduce oxidative markers and inflammatory gene expression under stress conditions.

A few studies show topical products containing safflower extracts might improve elasticity, hydration, and wrinkle appearance. However, replication and formulation-specific details are needed to confirm these effects broadly.

People with Asteraceae allergies (marigold, chamomile) may react to safflower extracts. Be sure to patch test.

Learn more about Carthamus Tinctorius Flower Extract

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Where it's from

Zymogen is a Singaporean brand

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Verified by SkinSort

We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.

The data we've presented on this page has been verified by a member of the SkinSort Team.

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· Updated July 15, 2025 Added by ktmgiu