Overview
What it is
Prescription with 9 ingredients that contains retinoid and Vitamin E
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils or silicones
Fun facts
Orion Pharma is from Finland. This product is used in 5 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Explained
Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.
All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.
This is why tretinoin is so effective; it gets to work immediately on the skin.
Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.
Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.
It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Read about a form of retinoid you can purchase at the store, retinol.
Learn more about TretinoinTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Cetyl AlcoholCetyl Palmitate is a wax-ester that pulls triple duty as an emollient, thickener, and emulsion enhancer.
It helps enhance the texture of products by giving a smooth, silky feel while helping to stabilize the formula. The emollient action softens skin and reduces moisture loss.
This ingredient is considered safe and human testing of concentrations between 2.5-2.7% were found minimal irritation. Just know, there have been very rare cases of the palmitate family causing contact dermatitis.
This ingredient may not be fungal acne safe because it contains a C16 ester (palmitic acid) that falls into the C11-24 range that Malassezia can feed on.
Learn more about Cetyl PalmitatePropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolSodium Lauryl Sulfate (SLS) is a surfactant, cleansing agent, and foaming agent. You'll find it in a wide range of products from shampoos to face cleansers.
It:
The Cosmetic Ingredient Review Panel has assessed it in 1983, 2002, and 2005 and found it to be safe in formulations at low concentrations.
SLS is a well-documented skin irritant at higher concentrations or with prolonged exposure. It's actually the gold standard positive control used in dermatological patch testing, meaning doctors use it because they know it will cause a reaction in people.
In one large study of 43,000 patiences tested with 0.25% SLS, about 22% showed some level of reactivity. It increases transepidermal water loss that disrupts your outermost layer of skin.
Face cleansers often pair this ingredient with mild co-surfactants like Cocamidopropyl Betaine to buffer its harshness.
Just so you know, SLS does not trigger true allergic contact dermatitis. This just means it can irritate your skin but doesn't cause your immune system to develop a lasting allergy to it.
Despite internet rumors, SLS is not considered a carcinogen by any major regulatory body.
Learn more about Sodium Lauryl SulfateMethylparaben is a synthetic preservative and one of the most widely used in the world. It has a simple, but important job: prevent your products from going bad by stopping bacteria, yeast, and mold from growing.
Typical use levels are low, often 0.1-0.3%.
This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.
In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.
Here's the science behind the noise behind parabens/hormones as well:
Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.
You get a stronger estrogenic effect from eating tofu, actually.
It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.
There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.
But as it stands today, this ingredient is considered safe at permitted levels.
Learn more about MethylparabenPropylparaben is a preservative and one of the most widely used members of the paraben family (it's been used in cosmetics for over a century now).
It works by disrupting microbial cell membranes and enzymes, and is a broad-spectrum protector that works exceptionally well against molds, yeasts, and gram-positive bacteria.
You'll likely see it paired with methylparaben to cover the full range (including gram-negative bacteria).
This ingredient is effective at low concentrations (~0.2-0.5%) and stable across a wide pH range (4.5-7.5 pH). It's effectiveness drops off above pH 8 and it can lose potency when combined with non-ionic surfactants like polysorbate 80 due to micellization.
The regulatory bodies have concluded this ingredient to be safe as used in cosmetics. The EU has capped it at 0.14% and combined parabens are not to exceed 0.8%.
While parabens do cross the stratum corneum, only about 1% remains for absorption into the body. This is because most of it is metabolized within living skin.
Learn more about PropylparabenWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
Orion Pharma is a Finnish brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated May 30, 2026 • Added by nestaa