Differin Adapalene Gel 0.1% Acne Treatment Versus Deriva Adaplene Microspheres Plus Clindamycin Phosphate Gel
Updated on February 21, 2025
Overview
What they are
These products are both fungal acne (malassezia) safe . They have a total of 1 ingredients in common
Cool Features
They both contain retinoid
Suited For
They're both likely to be good for fighting acne, anti aging, oily skin, reducing pores, scar healing and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
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Ingredient Info
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Deriva Adaplene Microspheres Plus Clindamycin Phosphate Gel 2 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Deriva Adaplene Microspheres Plus Clindamycin Phosphate Gel 2 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adapalene is a type of retinoid and common acne treatment.
It has been found to be as effective as other retinoids while causing less irritation.
Retinoids are the gold-standard for anti-aging due to the decades of research backing up their benefits:
You can buy adapalene over the counter, or in-store, in concentrations of 0.1% in gel form. 0.1% lotion or cream and 0.3% gel are only available with a prescription.
Learn more about AdapaleneIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Deriva Adaplene Microspheres Plus Clindamycin Phosphate Gel 2 ingredients

Reviews
Here's what our community thinks
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Honestly I was skeptical because it took my skin the FULL 12+ weeks to adjust to this. It was my first time using a retinoid and the purging was rough, but genuinely I’ve never seen my skin look so good after the purging ended. It absorbs well and a little goes a long way. I had to stop using it because I got too crazy with actives and I messed up my skin barrier super bad, but I’m hoping I can go Show more
I've been using this on and off for around 2 years. I thought this was going to help my acne, but looking back at pictures I actually think it's made my acne worse! It's made my acne areas really inflamed and red with angry spots. Think it's time to cut it out of my routine... Given it 2 stars as it soaks in pretty fast and is hydrating.