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Curology Custom Formula (Tretinoin 0.009%, Clindamycin 1%, Azelaic Acid 9%) Versus Curology Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)

Prescription
Prescription
American Brand United States
American Brand United States

Overview

What they are

These products are both cruelty-free and reef safe prescription. They have a total of 2 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Custom Formula (Tretinoin 0.009%, Clindamycin 1%, Azelaic Acid 9%)
Tretinoin
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 3 Benefits 2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Clindamycin Phosphate

Clindamycin Phosphate is a perscription ingredient used to treat acne.

Azelaic Acid Buffering, Masking
Helps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon
5 Benefits

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)
Tretinoin
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 3 Benefits 2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Azelaic Acid Buffering, Masking
Helps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon
5 Benefits

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Aloe Barbadensis Leaf Juice Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
2 Benefits

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Triethylene Glycol Masking, Perfuming
Fragrance Icon
FragranceFragrance Icon

Triethylene Glycol is a fragrance.

Unknown Full details ->
BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Loved

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All forms of OTC retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
Buffering, Masking
Loved

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.

Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.

One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people. It is also non-comedogenic, meaning that it will not clog pores.

Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.

Learn more about Azelaic Acid

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Custom Formula (Tretinoin 0.009%, Clindamycin 1%, Azelaic Acid 9%)
3
liked
mixed
disliked
not rated
Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)
6
1
6
1
liked
mixed
disliked
not rated

When to use

49 Routines
6% use in am
94% use in pm
84% use every day
When to use See routines that use it ->
14 Routines
0% use in am
100% use in pm
79% use every day