OPI Nature Strong Natural Origin Lacquer
A nail care with 25 ingredients, including exfoliants and vitamin E.
Overview
What it is
Nail care with 25 ingredients that contains exfoliants and Vitamin E
Cool Features
It is vegan, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, oily skin, reducing pores and dark spots
Free From
It doesn't contain any common allergens, oils, parabens, silicones or sulfates
Fun facts
OPI is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Butyl Acetate
MaskingEthyl Acetate
PerfumingNitrocellulose
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Acetyl Tributyl Citrate
MaskingAlcohol
AntimicrobialStearalkonium Bentonite
Gel FormingIsopropyl Alcohol
SolventDiacetone Alcohol
MaskingSorbic Acid
PreservativeHexanal
MaskingLithothamnion Calcareum Extract
Skin ConditioningPhosphoric Acid
BufferingMannitol
HumectantCI 77120
Cosmetic ColorantSolum Diatomeae
AbrasiveZinc Sulfate
AntimicrobialSilica
AbrasiveN-Butyl Alcohol
PerfumingTocopherol
AntioxidantCI 77891
Cosmetic ColorantIron Oxides
CI 15850
Cosmetic ColorantCI 19140
Cosmetic ColorantCI 77510
Cosmetic ColorantButyl Acetate, Ethyl Acetate, Nitrocellulose, Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer, Acetyl Tributyl Citrate, Alcohol, Stearalkonium Bentonite, Isopropyl Alcohol, Diacetone Alcohol, Sorbic Acid, Hexanal, Lithothamnion Calcareum Extract, Phosphoric Acid, Mannitol, CI 77120, Solum Diatomeae, Zinc Sulfate, Silica, N-Butyl Alcohol, Tocopherol, CI 77891, Iron Oxides, CI 15850, CI 19140, CI 77510
Key Ingredients
Benefits
Concerns
Ingredients Explained
We don't have a description for Butyl Acetate yet.
Ethyl Acetate is a fragrance.
We don't have a description for Nitrocellulose yet.
We don't have a description for Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer yet.
Acetyl Tributyl Citrate is a fragrance.
This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Learn more about AlcoholWe don't have a description for Stearalkonium Bentonite yet.
Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.
This ingredient is an astringent alcohol. Astringent alcohols may also irritate skin as they high amounts may strip away your skin's natural oils.
Other types of astringent alcohols include:
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.
Learn more about Isopropyl AlcoholWe don't have a description for Diacetone Alcohol yet.
Sorbic Acid is a preservative that stops your product from spoiling by stopping microbes from growing.
As a preservative, it's kind of a specialist: it has a broad spectrum of activity against yeast and molds but is weaker against bacteria. That's why it's often paired with another preservative to cover that gap.
This ingredient is also pretty picky about pH; it performs best at pH 6.5 or below.
At the right pH level, sorbic acid is "active" and can slip through the outer wall of a microbe. Once inside, it turns the cell's interior more acidic to shut down the microbe from the inside.
The EU caps this ingredient at 0.6% while the CIR has concluded it's safe at concentrations up to 1%. It's most often used around 0.05-0.2% in cosmetics.
Though this ingredient is considered low-sensitizing and well-tolerated, a very small number of people may have a contact allergy to it. Be sure to patch test if you have a history of allergies towards preservatives.
Learn more about Sorbic AcidWe don't have a description for Hexanal yet.
We don't have a description for Lithothamnion Calcareum Extract yet.
Phosphoric acid is used to adjust the pH of products.
Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.
When found in aqueous solutions, mannitol tends to become acidic. This is because it loses a hydrogen ion. This is why mannitol can often be found with pH adjusting ingredients, such as sodium bicarbonate.
Fun fact: Mannitol can be found in foods as a sweetener. It can be naturally found in mushrooms, algae, fruits, and veggies.
Learn more about MannitolWe don't have a description for CI 77120 yet.
Solum Diatomeae is an exfoliant.
Zinc Sulfate has antimicrobial and astringent properties. It is created synthetically from zinc and sulfuric acid.
Despite having ‘sulfate’ in the name, it isn’t a surfactant or cleansing agent like sodium lauryl sulfate. Unlike those sulfates, zinc sulfate doesn’t have the same cleansing or foaming properties.
Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaN-Butyl Alcohol is a fragrance and is an alcohol.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolCi 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891This ingredient is a combination of red, black, and yellow iron oxide pigments. This combination of colors is usually found in foundation, because it results in a "skin" color.
The EU typically uses CI numbers for colorants when applicable, such as CI 77489. In the US, iron oxides are regulated as color additives and "iron oxides" is the most commonly used name in US cosmetic practice.
A 2021 paper looked at skincare formulations containing iron oxides and found that they reduced transmission of blue light when measured optically. In simple terms, the pigment particles helped block or scatter part of the visible light spectrum in lab testing and the authors suggest this could translate into better protection against blue-light-related skin effects.
There is also clinical and experimental research showing that tinted products containing iron oxides can reduce visible light-induced pigmentation:
Please note, whether a product reduces visible or blue light depends on things like:
In the EU's CosIng database, iron oxides are only listed as a colorant. CosIng groups ingredients by their main cosmetic role, such as colorant, preservative, or UV filter.
Though studies say iron oxides can "attenuate blue light", they're describing an optical property and not an officially recognized cosmetic function.
So CosIng isn’t contradicting the research. It’s just classifying iron oxides by what they officially are: pigments that add color.
Learn more about Iron OxidesCi 15850 is the pigment color red. It is an azo dye and created synthetically.
Azo dyes need to be thoroughly purified before use. This allows them to be more stable and longer-lasting.
This ingredient is common in foundations, lipsticks, and blushes. This color is described as brown/orangey red.
It has many secondary names such as Red 6 and Red 7. According to a manufacturer, Red 6 usually contains aluminum.
Learn more about CI 15850CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Learn more about CI 19140This ingredient is used to impart a blue color. It is not water-soluble.
It goes by two different names:
1. Ferric Ferrocyanide: a synthetic dark blue pigment
2. Ferric Ammonium Ferrocyanide: a synthetic blue pigment, also called Prussian blue
In the EU, both of these colors must be labeled as 'CI 77510'.
Learn more about CI 77510Reviews
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Where it's from
OPI is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated February 2, 2026 • Added by elizabethannmarchena