What's inside
What's inside
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningPropanediol
Solvent
Tetrapeptide-21
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Caprooyl Tetrapeptide-3
Skin Protecting
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin Conditioning
Hexapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-40
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Hexapeptide-38
Skin Conditioning
Tetrapeptide-30
Skin Conditioning
Alpha-Arbutin
Antioxidant
Sodium PCA
Humectant
Sodium Hyaluronate
Humectant
1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
Emollient
Hydroxyacetophenone
Antioxidant
Water, Propanediol, Tetrapeptide-21, Acetyl Hexapeptide-8, Caprooyl Tetrapeptide-3, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Hexapeptide-9, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-40, Acetyl Tetrapeptide-2, Acetyl Hexapeptide-38, Tetrapeptide-30, Alpha-Arbutin, Sodium PCA, Sodium Hyaluronate, 1,2-Hexanediol, Caprylyl Glycol, Hydroxyacetophenone
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8
