Skin Actives Scientific T-Zone Serum
A facial treatment with 13 ingredients, including niacinamide and azelaic acid.
Overview
What it is
Facial treatment with 13 ingredients that contains azelaic acid and niacinamide
Cool Features
It is cruelty-free and fungal acne (malassezia) safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, silicones or sulfates
Fun facts
Skin Actives Scientific is from United States. This product is used in 1 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Explained
This ingredient is made by fermenting brown seaweed with Lactobacillus (the same family of microbes used to make yogurt).
Fermentation helps breaks down kelp's tough cell walls so the good stuff inside, like water-binding sugars (fucoidan and alginic acid), amino acids, and minerals like iodine, magnesium, and copper, can be useful to your skin.
The Lactobacillus also leaves behind its own helpful byproducts (think of these like the "leftovers" from fermentation) in the mix.
Topically, it mainly acts as a humectant with mild emollient properties. Fucoidan and brown-algae phenolics have well-documented antioxidant and anti-inflammatory activity.
In vitro studies on fermented-kelp broth have shown free-radical scavenging, tyrosinase inhibition, and support for keratinocyte viability.
There is nothing in this ingredient for Malassezia to feed on since Lactobacillus primarily produces water-soluble lactic acid and there are no oils in kelp.
Learn more about Lactobacillus/Kelp Ferment FiltratePotassium Azeloyl Diglycinate (PAD) comes from the condensation of azelaic acid mixed with glycine.
This ingredient has similar properties to azelaic acid; it can help reduce sebum production and soothe skin. PAD also inhibits tyrosinase activity to help brighten skin. Tyrosinase is an enzyme that controls melanin production.
A study from 2023 found 5% PAD combined with nicotinamide (a form of niacin) effectively reduced melanin production after 6 weeks.
Several studies from the 2010's also show PAD to be effective in alleviating symptoms of Rosacea.
Though this ingredient is considered a gentle active, higher amounts may result in irritation.
Unlike azelaic acid, this ingredient is water-soluble. This property makes it easier to formulate into skincare products.
Learn more about Potassium Azeloyl DiglycinateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterCamellia Sinensis Catechins is an antioxidant and is a fragrance.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideNobiletin is an antioxidant and is a preservative.
Fucoidan is a polysaccharide found in the cell walls of brown seaweed. It exhibits strong antioxidant properties.
Porphyridium Polysaccharide is an antioxidant.
We don't have a description for Arthrospira Extract yet.
Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolDiazolidinyl Urea is an antimicrobial preservative. It is commonly used to prevent bacterial, yeast, and mold growth.
Diazolidinyl Urea slowly breaks down into formaldehyde, an effective microbe killer but also a known allergen/carcinogen.
Some people who are allergic to imidazolidinyl urea also react to diazolidinyl urea. It ranked as the 14th most common allergen in patch tests from 2005โ06.
Safety reviews show that at concentrations under 0.5%, the formaldehyde released remains below the accepted safety limit, making it considered safe for cosmetic use.
Ultimately, its safety depends on individual skin sensitivity and personal comfort with formaldehyde-releasing preservatives.
Learn more about Diazolidinyl UreaMethylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.
Methylparaben can be synthetically created. It can also be found naturally in some fruits, such as blueberries.
Oftentimes, Methylparaben is combined with other parabens to help increase the shelf life.
The safety of Methylparaben is currently being studied. While ongoing studies are looking into the safety of parabens, the results have been very mixed. Some studies have not found Methylparaben to be harmful.
Learn more about MethylparabenPropylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.
This ingredient can be naturally found in plants and insects, but most of it is synthetically manufactured for human use. In cosmetics, it is usually created by reacting para-aminobenzoic acid and propanol (an alcohol).
You can usually find this ingredient in water-based products.
Parabens have come under controversy due to the claim they are hormone disruptors. Studies show conflicting results. We recommend speaking with a professional if you have any concerns.
Propylparaben is commonly found in food, medicine, and cosmetics.
Learn more about PropylparabenReviews
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Where it's from
Skin Actives Scientific is a American brand
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated February 27, 2026 • Added by BetsD