Padagis Sulfacetamide Sodium Topical Suspension USP 10% Lotion

Padagis Sulfacetamide Sodium Topical Suspension USP 10% Lotion

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Overview

What it is

Prescription with 14 ingredients

Suited For

It has ingredients that are good for dry skin

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils or sulfates

Fun facts

Padagis is from Israel. This product is used in 27 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Explained

This is not an INCI ingredient. It is an antiobiotic used to treat acne, seborrheic dermatitis, and certain skin infection. Other names for it include Plexion, Clenia, Prasion, and Avar.

We recommend speaking with a medical professional about using this ingredient.

Buffering

We don't have a description for Diethanolamine yet.

EDTA is the shortened name for ethylenediamine tetraacetic acid. It is a chelating agent and used to stabilize products.

Chelating Agents are used to prevent trace metal ions from binding to other ingredients. This can prevent unwanted reactions or changed efficacy of products.

Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Learn more about Hydroxyethylcellulose
Surfactant

We don't have a description for Lauramide DEA yet.

Preservative

Methylparaben is a synthetic preservative and one of the most widely used in the world. It has a simple, but important job: prevent your products from going bad by stopping bacteria, yeast, and mold from growing.

Typical use levels are low, often 0.1-0.3%.

This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.

In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.

Here's the science behind the noise behind parabens/hormones as well:

Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.

You get a stronger estrogenic effect from eating tofu, actually.

It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.

There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.

But as it stands today, this ingredient is considered safe at permitted levels.

Learn more about Methylparaben
Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

This ingredient is able to help dissolve active ingredients, including water. This gives it humectant properties.

It is soluble in water. The number '8' stands for the molecular weight of the ingredient.

Learn more about PEG-8
Skin Conditioning

Lauryl Laurate isn't fungal acne safe.

Humectant, Skin Conditioning, Solvent

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Learn more about Propylene Glycol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Emollient, Skin Conditioning

Simethicone is a silicone. It is an emollient and used to reduce foaming in a product. It is also often used to coat sunscreen ingredients for better spreadability.

This ingredient is created by mixing dimethylpolysiloxane and hydrated silica.

Masking

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Learn more about Sodium Chloride
Antioxidant, Preservative

Sodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.

As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.

Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

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Where it's from

Padagis is a Israeli brand

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The data we've presented on this page has been verified by a member of the SkinSort Team.

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ยท Updated November 3, 2025 Added by mackenziekennedy