Name: Adapaleno 0.1%
Brand: Medley
Rating: 5.00 (1 reviews)

Overview

What it is

Prescription with 9 ingredients that contains exfoliants and retinoid

Cool Features

It is fungal acne (malassezia) safe and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Medley is from Brazil. This product is used in 30 routines created by our community.

What's inside

Ingredients Explained

Adapalene

Adapalene is a third-generation topical retinoid and is best known for treating mild to moderate acne. It’s also commonly as for its brand name, Differin.

Adapalene has some great benefits:

You can buy over-the-counter adapalene at 0.1% gel strength. Higher concentrations require a prescription.

Oleyl adapalenate is a cosmetic-grade derivative of adapalene that does not require a prescription since it is considered a cosmetic ingredient.

Learn more about Adapalene

Carbomer

Emulsion Stabilising, Gel Forming

Carbomer is a high-molecular weight polymer of acrylic acid. It is used to form gels and thicken formulas.

Due to its large molecular size, carbomer has minimal skin penetration and is considered an inert ingredient.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Learn more about Carbomer

Sodium Anisate

Antimicrobial

Sodium Anisate comes from fennel. It is used as a preservative and to add flavoring.

Sodium Anisate has antimicrobial properties.

Disodium EDTA

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA

Sodium Hydroxide

Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

Imidazolidinyl Urea

Preservative

Imidazolidinyl Urea is a synthetic antimicrobial preservative. It works by slowly releasing small amounts of formaldehyde to keep bacteria, yeast, and mold from growing.

Just so you know, the formaldehyde released at typical use concentrations (up to 0.6% in the EU and typically 0.1-0.3% in the US) are tiny. The CIR Expert Panel has reaffirmed its safety as a cosmetic ingredient at current use concentrations in 2023. It's also not mutagenic in cell studies.

However, it is a known contact sensitizer with about a 1-2% contact allergy rate.

Other formaldehyde releasers include Diazolidinyl Urea or DMDM Hydantoin.

Learn more about Imidazolidinyl Urea

Silicon

Abrasive

Silicon is an abrasive as an INCI ingredient, meaning it has exfoliation properties.

If you see this ingredient in a tool, such as a brush, it is a material.

Propylene Glycol

Humectant, Skin Conditioning, Solvent

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Learn more about Propylene Glycol

Water

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water

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