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Padagis Tretinoin Cream, USP 0.05% Versus Retin-A (Tretinoin) Retin-A (Tretinoin) Cream 0.05%

Prescription
Prescription
Israeli Brand Israel
South African Brand South Africa

Updated on April 25, 2024

Overview

What they are

These products are both reef safe prescription. They have a total of 9 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
Cleansing, Emulsifying, Emulsion Stabilising

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

As an emollient, stearic acid helps soften skin. It aids the skin's protective barrier by preventing water loss. It also provides a gentle cleansing effect without stripping away natural oils.

Stearic acid may also be used to enhance the texture of products. It can add volume and stabilize ingredients such as water and oil. This can help water and oil ingredients from separating.

Sources of stearic acid include animal or vegetable fats/oils such as coconut or shea. It can be naturally found in butter, cocoa butter, shea butter, vegetable fats, and animal tallow.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

Learn more about Stearic Acid
Emollient, Masking

Isopropyl Myristate is an emollient, thickening agent, and texture enhancer. It is created from isopropyl alcohol and myristic acid.

It is used to help other ingredients be better absorbed. It is also an emollient and may help soften and hydrate the skin.

The comedogenic rating of this ingredient depends on the concentration. Lower amounts results in a lower rating.

Isopropyl Myristate may not be fungal acne safe. It can potentially worsen acne prone skin.

Learn more about Isopropyl Myristate
Emulsifying

Peg-40 Stearate is a waxy solid made up of polyethylene glycol and stearic acid. It is an emulsifier and cleanser. Emulsifiers help oils and water mix.

Stearic acid is a a fatty acid. Therefore, Peg-40 stearate may not be fungal-acne safe.

Emollient, Emulsifying, Emulsion Stabilising

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

Fatty Alcohols are most often used as an emollient or to thicken a product. Emollients help soothe and hydrate the skin by trapping moisture.

They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols. FDA allows products labeled "alcohol-free" to have fatty alcohols.

Learn more about Stearyl Alcohol
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Preservative

Sorbic Acid is a preservative. It is the most commonly used food preservative in the world.

Sorbic Acid is a natural antibiotic and highly effective at preventing the growth of fungus. It is less effective against bacteria.

Potassium Sorbate, another commonly-used preservative, is the potassium salt of Sorbic Acid.

Sorbic Acid may worsen eczema. We recommend speaking with a professional if you have any concerns.

Potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

Learn more about Sorbic Acid
BHT
Antioxidant, Masking

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Learn more about BHT
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

23 Routines
0% use in am
104% use in pm
61% use every day
515 Routines
2% use in am
98% use in pm
65% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Padagis Tretinoin Cream, USP 0.05% 9 ingredients

Tretinoin Cream, USP 0.05% hasn't been rated yet.
Rate it now

Retin-A (Tretinoin) Retin-A (Tretinoin) Cream 0.05% 9 ingredients

4.0 /5
from 2 ratings
Works Well (2) Great Value (1) Heavy (1)
chlolands's avatar

chlolands

12 months ago
Review

Never gave me the miracle results I've seen all over TikTok but served me well for the 3+ years I was on this.

#heavy
#works well
hmmh's avatar

hmmh

10 months ago
Review

Been on this for 4 years. It does not perform miracles but it does keep your skin youthful to some extent sans procedures. Worked on reducing inflammation and acne but dried my skin out, even after a full year of consistent use. With this, sunscreen is non-negotiable.

#great value
#drying
#irritating
#sticky