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Updated on July 18, 2023

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 10 ingredients in common

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Numbuzin No.3 Skin Softening Serum
Numbuzin No.3 Skin Softening Serum
Serum
South Korean Brand South Korea
Isntree TW-Real Bifida Ampoule
Isntree TW-Real Bifida Ampoule
Ampoule
South Korean Brand South Korea

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
No.3 Skin Softening Serum
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Galactomyces Ferment Filtrate Humectant
Helps hydrate Dry Skin  •  Not safe for Fungal Acne

Galactomyces Ferment Filtrate (GFF) is a yeast traditionally used to make the Japanese alcoholic beverage, sake.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Niacinamide Smoothing
Niacinamide  •  6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Peg-90 Humectant, Solvent
Not safe for Fungal Acne

Peg-90 isn't fungal acne safe.

Disliked Full details ->
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Squalane Emollient, Skin Conditioning
1 / 0
Helps hydrate Dry Skin

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Alteromonas Ferment Extract Skin Conditioning

Alteromonas Ferment Extract is derived from a bacteria from in deep sea water.

Silk Extract Skin Conditioning

We don't have a description for Silk Extract.

Unknown Full details ->
Goat Milk Extract

We don't have a description for Goat Milk Extract.

Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Panthenol Skin Conditioning
0 / 0
Helps reduce irritation

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

0 Com. / 0 Irr.
Adenosine Skin Conditioning
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Glycereth-26 Humectant
0 / 0

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

0 Com. / 0 Irr.
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Polyglyceryl-3 Distearate Emulsifying
Not safe for Fungal Acne

Polyglyceryl-3 Distearate isn't fungal acne safe.

Very Disliked Full details ->
Glyceryl Stearate Se Emulsifying
3 / 2
Not safe for Fungal Acne

Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.

3 Com. / 2 Irr.
Very Disliked Full details ->
Glyceryl Stearate Citrate Emollient, Emulsifying, Skin Conditioning
Not safe for Fungal Acne

Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.

Very Disliked Full details ->
Polyglyceryl-3 Methylglucose Distearate Emulsifying
Not safe for Fungal Acne

Polyglyceryl-3 Methylglucose Distearate is created from the diester of stearic acid and the condensation product of methylglucose and Polyglycerin-3.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Tropolone Skin Conditioning

We don't have a description for Tropolone.

Unknown Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
TW-Real Bifida Ampoule
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Niacinamide Smoothing
Niacinamide  •  6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Lactobacillus/Pumpkin Ferment Extract Skin Conditioning

We don't have a description for Lactobacillus/Pumpkin Ferment Extract.

Lactobacillus/Soybean Ferment Extract Skin Conditioning

This ingredient is created by fermenting soybean extract with the bacteria, lactobacillus.

Rice Ferment Filtrate Skin Conditioning
2 Benefits

Rice Ferment Filtrate is created by fermenting rice, or oryza sativa. A common name for this ingredient is sake, the traditional Japanese fermented rice alcoholic beverage.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydrolyzed Collagen Emollient, Humectant, Skin Conditioning
Helps with Anti-Aging

Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.

Salix Alba Bark Extract Astringent, Skin Conditioning, Soothing
Good for Oily Skin

Salix Alba Bark Extract comes from the white willow tree, which is native to Europe and Central Asia.

Origanum Vulgare Leaf Extract Skin Conditioning

We don't have a description for Origanum Vulgare Leaf Extract.

Unknown Full details ->
Cinnamomum Zeylanicum Bark Extract Antimicrobial, Antioxidant, Astringent
Antioxidant  •  Fragrance

Cinnamomum Zeylanicum Bark Extract is an antioxidant and is a fragrance.

Unknown Full details ->
Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Chamaecyparis Obtusa Leaf Extract Skin Conditioning

We don't have a description for Chamaecyparis Obtusa Leaf Extract.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Palmitoyl Oligopeptide Cleansing, Skin Conditioning
Peptide  •  Not safe for Fungal Acne

Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.

Copper Tripeptide-1 Skin Conditioning
Peptide  •  Helps with Anti-Aging

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Panthenol Skin Conditioning
0 / 0
Helps reduce irritation

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

0 Com. / 0 Irr.
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Scutellaria Baicalensis Root Extract Astringent, Humectant, Soothing
Good for Scar Healing

Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.

Illicium Verum Fruit Extract Perfuming, Skin Conditioning
Fragrance

Illicium Verum Fruit Extract is a fragrance.

Adenosine Skin Conditioning
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Liked

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning
Loved

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

lt is a humectant, meaning that it helps the skin attract and retain moisture.

Another benefit is the anti-inflammatory abilities. This means that it's great for sensitive, irritation-prone skin.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

Learn more about Panthenol
Skin Conditioning
Loved

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

No.3 Skin Softening Serum
12
5
8
3
liked
mixed
disliked
not rated
TW-Real Bifida Ampoule
20
4
3
2
liked
mixed
disliked
not rated

When to use

1,132 Routines
42% use in am
58% use in pm
93% use every day
When to use See routines that use it ->
86 Routines
38% use in am
62% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Numbuzin No.3 Skin Softening Serum 28 ingredients

4.1 /5
from 18 ratings
Works Well (3) Light (3) No Scent (2) Absorbs Well (2) Broke Me Out (2) Sticky (1)
cgi's avatar

cgi

4 months ago · Oily Skin
Review

numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish...

numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish serum.
i've only been using this since march of last year and it has been a game-changer ever since. i feel a bit dramatic when i say this, but i genuinely have seen a big difference in my skin using this compared to any other serum i've ever used. it blended in with my routine sooo unbelievably well. i don't know what type of witchcraft or sorcery is in this, but this product is a blessing and it's money VERY well-spent. beautiful bottle, it's like glass or something. it's a bit expensive, but you get so much product that'll last you way longer than a year. like i've had this since MARCH, and i still have over half the bottle left even though i use 3 drops every single night religiously.
it's hydrating, makes my skin very smooth (as it should), and has gone above and beyond in improving my skin texture. it miraculously decreased so many of the little bumps i get. it also absorbs very well under my base, literally just cleared my skin and boosted the glass skin look. i love this serum please buy it.

anniec's avatar

anniec

4 months ago · Dry Skin
Review

I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it...

I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it didn't fix was the stubborn closed comedones on my jaw and chin which wont go away no matter what.

Isntree TW-Real Bifida Ampoule 29 ingredients

5.0 /5
from 1 rating
Marifsts's avatar

Marifsts

8 months ago · Combination Skin
Review

Worthy a lot
I'm using as a dupe to Lancome Gentifique serum and I love it, my skin is soft and feels healthier, I can describe, but is a perfect dupe