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Overview

Cool Features

They both contain hyaluronic acid and retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin and brightening skin

Free From

They both do not contain any oils or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Altreno Tretinoin 0.05%
Altreno Tretinoin 0.05%
Prescription
American Brand United States
SkinBetter Science AlphaRet Overnight Cream
SkinBetter Science AlphaRet Overnight Cream
Night Moisturizer
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Tretinoin 0.05%
Tretinoin
Retinoid  •  3 Benefits  •  2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol  •  Fragrance  •  Preservative  •  6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
BHT Antioxidant, Masking
Antioxidant

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Methylparaben Preservative
0 / 0
Preservative  •  Paraben  •  2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Paraffinum Liquidum Emollient, Skin Protecting, Solvent
0-2 / 0
2 Concerns

Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.

0-2 Com. / 0 Irr.
Very Disliked Full details ->
Octoxynol-9 Emulsifying
0-1 / 0

Octoxynol-9 are part of a group called ethoxylated alkyl phenols. Octoxynols are usually found in hair-coloring products.

0-1 Com. / 0 Irr.
Unknown Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0
Hyaluronic Acid

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Collagen Moisturising, Skin Conditioning
Helps with Anti-Aging

Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.

Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
AlphaRet Overnight Cream
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Glycolate Buffering

We don't have a description for Sodium Glycolate.

Unknown Full details ->
Glycolic Acid Buffering
AHA  •  7 Benefits  •  2 Concerns

Glycolic Acid is arguably the most famous AHA with research to back up its benefits. Its main role is to peel the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and look more even.

Cetearyl Olivate
Not safe for Fungal Acne

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

Disliked Full details ->
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Isohexadecane Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Sorbitan Olivate Emulsifying
Not safe for Fungal Acne

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Ascorbyl Tetraisopalmitate Antioxidant, Emollient, Skin Conditioning
Vitamin C  •  Antioxidant  •  4 Benefits  •  Not safe for Fungal Acne

Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or pure Vitamin C.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Ceresin Emulsion Stabilising
0 / 0

Ceresin is a wax derived from ozokerite. It is an alternative to beeswax.

0 Com. / 0 Irr.
Disliked Full details ->
Glycol Palmitate Emulsifying, Skin Conditioning
Not safe for Fungal Acne

Glycol Palmitate isn't fungal acne safe.

Unknown Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Niacinamide Smoothing
Niacinamide  •  6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Squalane Emollient, Skin Conditioning
1 / 0
Helps hydrate Dry Skin

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Ethyl Lactyl Retinoate Abrasive, Skin Conditioning
Exfoliant  •  Retinoid  •  7 Benefits  •  2 Concerns

Ethyl Lactyl Retinoate is a form of retinoid and is an exfoliant. It can be good for be good for oily skin. It can help to improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne. It can be bad for dry skin and cause irritation.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide  •  Not safe for Fungal Acne

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tetrapeptide-7 Skin Conditioning
Peptide  •  Not safe for Fungal Acne

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

Ceramide NP Skin Conditioning
Ceramide  •  4 Benefits

Ceramide NP is a type of ceramide.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid  •  4 Benefits  •  May cause irritation

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Ubiquinone Antioxidant, Skin Conditioning
Antioxidant  •  Helps with Anti-Aging

Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.

Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3
Vitamin E  •  Antioxidant  •  4 Benefits  •  May cause irritation

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Bisabolol Masking, Skin Conditioning, Soothing
Helps reduce irritation

Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.

Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0
Vitamin E  •  Antioxidant  •  Helps brighten skin

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Superoxide Dismutase Antioxidant, Skin Conditioning
Antioxidant

Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.

Butyrospermum Parkii Butter Skin Conditioning
Helps hydrate Dry Skin  •  2 Concerns

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Very Disliked Full details ->
Allantoin Glycyrrhetinic Acid Skin Protecting, Soothing

We don't have a description for Allantoin Glycyrrhetinic Acid.

Unknown Full details ->
Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Panthenol Skin Conditioning
0 / 0
Helps reduce irritation

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

0 Com. / 0 Irr.
Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant  •  5 Benefits

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Linoleic Acid Cleansing, Emollient, Skin Conditioning
Helps hydrate Dry Skin  •  3 Concerns

Linoleic Acid is Vitamin F and a fatty acid. It is an emollient and helps thicken texture. Linoleic acid helps with hydrating skin and nourishing the skin's barrier. The top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.

Cholesterol Emollient, Emulsifying, Skin Conditioning
0 / 0
2 Benefits

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

0 Com. / 0 Irr.
Linolenic Acid Cleansing, Emollient, Perfuming
Fragrance  •  Not safe for Fungal Acne

Linolenic Acid is a fatty acid. Our bodies need to consume this to use it. Linolenic Acid helps condition and restore skin. It is also used to treat inflammation and hyperpigmentation.

Magnesium Aluminum Silicate Absorbent
0 / 0

Magnesium Aluminum Silicate is a type of silica. It comes from naturally occuring minerals such as silicate ores and clay.

0 Com. / 0 Irr.
Disliked Full details ->
Dimethyl Isosorbide Solvent

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0
Silicon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0
Not safe for Fungal Acne

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0
Not safe for Fungal Acne

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Steareth-2 Emulsifying
2 / 2

Steareth-2 is a waxy compound used to emulsify ingredients. It is created from polyethylene glycol and stearyl alcohol.

2 Com. / 2 Irr.
Very Disliked Full details ->
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Acacia Senegal Gum Masking

We don't have a description for Acacia Senegal Gum.

Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Hydrated Silica Abrasive, Absorbent
Exfoliant

Hydrated Silica is a type of silicon dioxide. It is called 'hydrated silica' because it is silica with extra bonded water atoms.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0
Not safe for Fungal Acne

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Phenoxyethanol Preservative
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
CI 77891 Cosmetic Colorant

Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Tretinoin 0.05%
5
6
1
liked
mixed
disliked
not rated
AlphaRet Overnight Cream
23
8
18
3
liked
mixed
disliked
not rated

When to use

413 Routines
2% use in am
98% use in pm
75% use every day
When to use See routines that use it ->
53 Routines
2% use in am
98% use in pm
92% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Altreno Tretinoin 0.05% 12 ingredients

4.8 /5
from 5 ratings
borntohula85's avatar

borntohula85

8 months ago · Oily Skin
Review

Tretinoin is the best thing that has ever happened to my skin. While retinization isn’t easy, my skin has never looked better than now at 38.

Sbutler85's avatar

Sbutler85

10 months ago · Normal Skin
Review

the bomb.com

SkinBetter Science AlphaRet Overnight Cream 52 ingredients

1.0 /5
from 1 rating
Expensive (1)
Erthrud's avatar

Erthrud

4 months ago · Oily Skin
Review

Why would anyone pay for this instead of tretinoin?!