Overview
What it is
Facial treatment with 9 ingredients that contains benzoyl peroxide
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for fighting acne, dry skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
Fun facts
ISDIN is from Spain. This product is used in 7 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Explained
Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.
It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.
On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.
One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.
BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.
The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.
Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.
A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.
Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!
Learn more about Benzoyl PeroxideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceWe don't have a description for Acrolein/Acrylic Acid Copolymer yet.
Simethicone is a silicone. It is an emollient and used to reduce foaming in a product. It is also often used to coat sunscreen ingredients for better spreadability.
This ingredient is created by mixing dimethylpolysiloxane and hydrated silica.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAWe don't have a description for Sodium Succinate yet.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
ISDIN is a Spanish brand
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated May 26, 2025 • Added by anaisabelnunes