Encube Clobetasol Propionate Ointment USP, 0.05%

Encube Clobetasol Propionate Ointment USP, 0.05%

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Overview

What it is

Prescription with 4 ingredients

Cool Features

It is reef safe

Suited For

It has ingredients that are good for dry skin

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates

Fun facts

Encube is from India. This product is used in 4 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Benefits

Concerns

Ingredients Explained

This is a medical ingredient used to treat skin conditions such as eczema, contact dermatitis, seborrheic dermatitis, steroid responsive dermatosis, and psoriasis.

We recommend speaking with a medical professional about using this ingredient.

Humectant, Skin Conditioning, Solvent

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Learn more about Propylene Glycol
Emulsifying

Sorbitan Sesquioleate is derived from sorbitol and oleic acid. It is an emulsifier and prevents ingredients from separating.

Specifically, this ingredient is a water-in-oil emulsifier, meaning it helps water dissolve into oil.

Some studies suggest this ingredient may cause irritation in some people. If you are unsure, it is best to patch test.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe due to the oleic acid. In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

Learn more about Sorbitan Sesquioleate
Emollient

Petrolatum is more commonly known as petroleum jelly. It is created by mixing waxes and mineral oils.

This ingredient is effective at reducing water loss by 99%. This is because it is an occlusive. Occlusives create a hydrophobic barrier on the skin to prevent evaporation. This property makes it great for hydrating dry skin.

Pro tip: Use occlusives, such as this ingredient, on damp skin for the best results.

The quality or origin of petrolatum is only known when disclosed by the brand. Most cosmetic petrolatum has gone through several purification stages.

Another benefit of occlusives is it protects your skin against infection or allergies.

Petrolatum is fungal acne safe. It is a hydrocarbon with no fatty acid structure, so Malassezia cannot metabolize it. In-vitro studies support negligible growth stimulation as well.

It's also worth noting that petrolatum has a comedogenic rating of 0. In updated rabbit ear testing (and in human testing), petrolatum was found to be not comedogenic. This means it didn’t promote comedone formation in standard models.

Learn more about Petrolatum

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Where it's from

Encube is a Indian brand

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· Updated January 28, 2026 Added by Frans