

Dr. Diamond's Metacine Instafacial Plasma Bioactive Growth Factor Serum
A serum with 17 ingredients, including peptides.
Overview
What it is
Serum with 17 ingredients that contains peptides
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Dr. Diamond's Metacine is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin Conditioning1,2-Hexanediol
Skin ConditioningNicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1
Skin ConditioningN-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin ConditioningSh-Oligopeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningSh-Polypeptide-1
Skin ConditioningSh-Polypeptide-11
Sh-Polypeptide-9
Skin ConditioningAcetyl Hexapeptide-8
HumectantAcetyl Glutamine
Skin ConditioningCopper Tripeptide-1
Skin ConditioningRaphanus Sativus Root Extract
AstringentBacillus
Skin ConditioningSodium Stearoxy Pg-Hydroxyethylcellulose Sulfonate
Ethylhexylglycerin
Skin ConditioningCaprylyl Glycol
EmollientWater, 1,2-Hexanediol, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-8, Acetyl Glutamine, Copper Tripeptide-1, Raphanus Sativus Root Extract, Bacillus, Sodium Stearoxy Pg-Hydroxyethylcellulose Sulfonate, Ethylhexylglycerin, Caprylyl Glycol
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about Water1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Ā
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesĀ
Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is a peptide.
N-Prolyl Palmitoyl Tripeptide-56 Acetate is a peptide.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itās often referred to as a āBotox-likeā ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itās not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnāt a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8We don't have a description for Acetyl Glutamine yet.
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesnāt turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isnāt backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1We don't have a description for Raphanus Sativus Root Extract yet.
We don't have a description for Bacillus yet.
We don't have a description for Sodium Stearoxy Pg-Hydroxyethylcellulose Sulfonate yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolReviews
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Where it's from
Dr. Diamond's Metacine is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usĀ· Published October 4, 2025 • Added by almapaz