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T3 Mycin Clindamycin Lotion

Name: Mycin Clindamycin Lotion
Brand: T3

Facial treatment with 3 ingredients

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Ingredients List

Clindamycin Phosphate

Methylparaben

Preservative

0 / 0 Paraben Icon

Propylparaben

Preservative

0 / 0 Paraben Icon

Clindamycin Phosphate, Methylparaben, Propylparaben

Benefits

Concerns

Ingredients Explained

Clindamycin Phosphate

Clindamycin Phosphate is a prescription antiobiotic used to treat acne.

We recommend speaking with a medical professional about using this ingredient.

Methylparaben

Preservative

Methylparaben is a synthetic preservative and one of the most widely used in the world. It has a simple, but important job: prevent your products from going bad by stopping bacteria, yeast, and mold from growing.

Typical use levels are low, often 0.1-0.3%.

This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.

In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.

Here's the science behind the noise behind parabens/hormones as well:

Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.

You get a stronger estrogenic effect from eating tofu, actually.

It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.

There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.

But as it stands today, this ingredient is considered safe at permitted levels.

Learn more about Methylparaben

Propylparaben

Preservative

Propylparaben is a preservative and one of the most widely used members of the paraben family (it's been used in cosmetics for over a century now).

It works by disrupting microbial cell membranes and enzymes, and is a broad-spectrum protector that works exceptionally well against molds, yeasts, and gram-positive bacteria.

You'll likely see it paired with methylparaben to cover the full range (including gram-negative bacteria).

This ingredient is effective at low concentrations (~0.2-0.5%) and stable across a wide pH range (4.5-7.5 pH). It's effectiveness drops off above pH 8 and it can lose potency when combined with non-ionic surfactants like polysorbate 80 due to micellization.

The regulatory bodies have concluded this ingredient to be safe as used in cosmetics. The EU has capped it at 0.14% and combined parabens are not to exceed 0.8%.

While parabens do cross the stratum corneum, only about 1% remains for absorption into the body. This is because most of it is metabolized within living skin.

Learn more about Propylparaben