Skin Medicinals SM75 Tranexamic Acid/Azelaic Acid/Niacinamide 8%/10%/2%

Name: SM75 Tranexamic Acid/Azelaic Acid/Niacinamide 8%/10%/2%
Brand: Skin Medicinals

A prescription with 3 ingredients, including niacinamide, azelaic acid, and tranexamic acid.

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Overview

What it is

Prescription with 3 ingredients that contains azelaic acid, niacinamide and tranexamic acid

Cool Features

It is fungal acne (malassezia) safe and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Skin Medicinals is from United States. This product is used in 13 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

3

Active Ingredients

Tranexamic Acid 8%

Astringent

Azelaic Acid 10%

Buffering

Niacinamide 2%

Smoothing

Active Ingredients: Tranexamic Acid 8%, Azelaic Acid 10%, Niacinamide 2%
Inactive Ingredients:

Key Ingredients

Benefits

Ingredients Explained

Tranexamic Acid

Astringent, Skin Conditioning

Tranexamic Acid (TXA) is a synthetic lysine derivative that is becoming one of the most exciting brightening ingredients in skincare.

Originally used in medicine as an anti-hemorrhagic agent, its skin brightening potential was discovered by accident; patients taking it orally started noticing their melasma was fading.

Unlike most brighteners that target tyrosinase (the enzyme that synthesizes melanin), TXA works further upstream. It basically blocks your cells from receiving the signal to produce pigment.

This makes it one of the rare actives that works on three pathways at once:

This makes it effective for treating melasma, post-inflammatory hyperpigmentation (PIH), and sun-induced dark spots.

The most effective cosmetic concentration sits between 2-5% and going higher doesn't boost results.

Side effects are generally mild; occasional irritation, flaking, or dryness have been reported at the start of use. Overall, this ingredient is pretty well tolerated, even by sensitive skin types.

Another perk of this ingredient is that it does not cause photosensitivity, so it's safe to use in the AM and PM.

Learn more about Tranexamic Acid

Azelaic Acid

Buffering, Masking

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Learn more about Azelaic Acid

Niacinamide

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide