Skin + Me Custom Daily Dose

Skin + Me Custom Daily Dose

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Overview

What it is

Prescription with 7 ingredients that contains azelaic acid, niacinamide and retinoid

Cool Features

It is cruelty-free, fungal acne (malassezia) safe, and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Skin + Me is from United Kingdom. This product is used in 176 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin

Clindamycin Phosphate is a prescription antiobiotic used to treat acne.

We recommend speaking with a medical professional about using this ingredient.

Buffering, Masking

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Learn more about Azelaic Acid
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide

Metronidazole is a prescription medication. It is used to treat rosacea.

We recommend speaking with a professional about this ingredient.

Stabilising

Hydroquinone is a classic ingredient dermatologists use to fade dark spots (things like melasma, acne marks, sun spots, and freckles).

It works in two ways:
1. By blocking an enzyme called tyrosinase; your skin uses this to make melanin, or the pigment that causes dark spots.
2. By interfering with the pigment making cells themselves so less pigment shows up over time

Just know this ingredient fades spots near the surface of skin and not the deeper ones. It's usually used at 2-4% / twice a day for 3 months, and ALWAYS with sunscreen.

This ingredient is usually well tolerated with short-term use under medical guidance. But possible reactions include irritation, contact dermatitis, and lightening of the skin around the spot you're treating.

You might hear hydroquinone called "cancer-causing". That concern comes from studies where rats were fed high oral doses; no skin cancer cases have been linked to it after more than 50 years of people putting it on their skin.

Long-term, high-strength, and unsupervised use can lead to a condition called ochronosis. This is where the skin turns blue-grey color and sometimes causes nails to turn dark as well.

The rules around it vary by country.

The EU bans it in regular cosmetics and it is prescription only in the US, EU, Japan, Canada, and Australia. Anything you see on the shelf without a prescription is technically not allowed.

Check out the European alternative to hydroquinone here.

SkinSort would like to remind friends from around the world that all skin tones are beautiful!

Learn more about Hydroquinone

Hydrocortisone is the name for the hormone cortisol when used in medication.

It is medication and not technically a cosmetic ingredient. Most countries allow topical creams to contain up between 0.05 - 2.5% (depending on the country) of hydrocortisone without a prescription. Higher amounts usually require a prescription from a professional.

Hydrocortisone can help relieve rashes, eczema, itching, and other inflammation induced skin conditions.

We recommend speaking with a professional about using this ingredient.

Learn more about Hydrocortisone

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Where it's from

Skin + Me is a British brand

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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.

The data we've presented on this page has been verified by a member of the SkinSort Team.

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ยท Updated October 11, 2025 Added by Leandra_