Best Prescription that are good for Acne and Oily Skin
Explore the top prescription for oily skin and acne with detailed ingredient breakdowns, usage guidelines, and reviews from skincare lovers like you.
Top products
Galderma
Epiduo (New)
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne
- it is reef safe
- it is not fungal acne (malassezia) safe
Galderma
Differin Cream
prescription that contains retinoid.
Details
This product contains 10 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
- it does contain parabens
- it is likely to be good for dry skin
- it is not fungal acne (malassezia) safe
Taro
Adapalene 0.3% Gel
prescription that contains retinoid.
Details
This product contains 9 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
- it does contain parabens
- it is fungal acne (malassezia) safe
Galderma
Epiduo Forte Gel
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne and dry skin
- it is reef safe
- it is not fungal acne (malassezia) safe
Galderma
Epiduo
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne and dry skin
- it is reef safe
- it is not fungal acne (malassezia) safe
iNova Pharmaceuticals
ReTrieve Cream
prescription that contains retinoid and vitamin e.
Details
This product contains 13 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing, dark spots and better texture
- it is reef safe
- it is not fungal acne (malassezia) safe
Galderma
Epiduo Gel 0.1%/2.5%
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 14 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne and dry skin
- it is reef safe
- it is not fungal acne (malassezia) safe
Apostrophe
Tretinoin 0.025% Prescription
prescription that contains niacinamide, retinoid and vitamin e.
Details
This product contains 20 ingredients.
- it doesn't contain any harsh alcohols, common allergens, parabens or sulfates
- it does contain fragrances, oils and silicones
- it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe
The Agency
Future Formula
vegan and cruelty-free prescription that contains niacinamide, retinoid and vitamin e.
Details
This product contains 13 ingredients.
- it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
- it does contain fragrances
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
- it is reef safe and reef safe
- it is not fungal acne (malassezia) safe
Curology
Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)
cruelty-free prescription that contains niacinamide and vitamin e.
Details
This product contains 13 ingredients.
- it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
- it does contain fragrances
- it is likely to be good for fighting acne, sensitive skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe

Skin Medicinals
SM63 Tretinoin/Niacinamide, Sodium Hyaluronate 0.5%
prescription that contains hyaluronic acid, niacinamide and retinoid.
Details
This product contains 4 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
- it is fungal acne (malassezia) safe and reef safe
Skin + Me
Custom Daily Dose
prescription that contains niacinamide and retinoid.
Details
This product contains 7 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
- it is fungal acne (malassezia) safe and reef safe
Curology
Custom FormulaRX (Zinc pyrithione 0.25%, Clindamycin 1%, Niacinamide 4%)
cruelty-free prescription that contains niacinamide.
Details
This product contains 3 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne
- it is fungal acne (malassezia) safe and reef safe
Valeant
Biacna Topical Gel
prescription that contains aha and retinoid.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
- it does contain parabens
- it is likely to be good for fighting acne, brightening skin, reducing pores, scar healing and better texture
- it is not fungal acne (malassezia) safe
Dermatica
Custom Formula (Tretinoin 0.015%, Niacinamide 4%)
prescription that contains ceramides, hyaluronic acid, niacinamide, retinoid and vitamin e.
Details
This product contains 28 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
- it does contain silicones
- it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe
Apostrophe
Custom Prescription
prescription that contains niacinamide and retinoid.
Details
This product contains 9 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe
Apostrophe
Tretinoin 0.018% Prescription
prescription that contains niacinamide, retinoid and vitamin e.
Details
This product contains 20 ingredients.
- it doesn't contain any harsh alcohols, common allergens, parabens or sulfates
- it does contain fragrances, oils and silicones
- it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe
Musely
1 Type
Anti Aging Cream
prescription that contains exfoliants, hyaluronic acid, niacinamide, retinoid and vitamin e.
Details
This product contains 14 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
- it does contain silicones
- it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, reducing pores, scar healing and dark spots
- it is fungal acne (malassezia) safe and reef safe
Dermatica
Custom Formula (Adapalene 0.1%, Niacinamide 4%, Clindamycin 1%)
prescription that contains ceramides, hyaluronic acid, niacinamide, retinoid and vitamin e.
Details
This product contains 29 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
- it does contain silicones
- it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and scar healing
- it is reef safe
- it is not fungal acne (malassezia) safe
Skin Software
Prescription Tretinoin 0.018%
vegan prescription that contains hyaluronic acid, niacinamide, retinoid and vitamin e.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
- it does contain fragrances
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing and dark spots
- it is reef safe
- it is not fungal acne (malassezia) safe
Bausch Health
Cabtreo Topical Gel 1.2%/0.15%/3.1%
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 7 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne
- it is fungal acne (malassezia) safe and reef safe
Curology
Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)
cruelty-free prescription that contains niacinamide, retinoid and vitamin e.
Details
This product contains 14 ingredients.
- it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
- it does contain fragrances
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
- it is reef safe
- it is not fungal acne (malassezia) safe
Encube
Adapalene Gel 0.3%
prescription that contains retinoid.
Details
This product contains 9 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
- it does contain parabens
- it is fungal acne (malassezia) safe
Padagis
Adapalene And Benzoyl Peroxide Topical Gel
prescription that contains benzoyl peroxide and retinoid.
Details
This product contains 12 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne and dry skin
- it is reef safe
- it is not fungal acne (malassezia) safe
Curology
Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)
cruelty-free prescription that contains niacinamide, retinoid and vitamin e.
Details
This product contains 14 ingredients.
- it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
- it does contain fragrances
- it is likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
- it is reef safe
- it is not fungal acne (malassezia) safe
Dermatica
Custom Formula (Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%)
vegan prescription that contains ceramides, hyaluronic acid, niacinamide and vitamin e.
Details
This product contains 28 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
- it does contain silicones
- it is likely to be good for anti aging, dry skin, brightening skin and sensitive skin
- it is reef safe
- it is not fungal acne (malassezia) safe
Curology
Custom Formula (Tretinoin 0.035%, Tranexamic Acid 5%, Niacinamide 4%)
cruelty-free prescription that contains niacinamide and retinoid.
Details
This product contains 3 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing and dark spots
- it is fungal acne (malassezia) safe and reef safe
Alembic
Adapalene Gel 0.3%
prescription that contains retinoid.
Details
This product contains 8 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates
- it does contain parabens
- it is fungal acne (malassezia) safe
Ichthyol
Cordes VAS Tretinoin Creme
prescription that contains aha, retinoid and vitamin c.
Details
This product contains 13 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for anti aging, brightening skin, reducing pores, scar healing, dark spots and better texture
- it is reef safe
- it is not fungal acne (malassezia) safe
Deriva
Adaplene Microspheres Plus Clindamycin Phosphate Gel
prescription that contains retinoid.
Details
This product contains 2 ingredients.
- it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
- it is likely to be good for fighting acne
- it is fungal acne (malassezia) safe and reef safe