Dermatica Custom Formula (Adapalene 0.1%, Azelaic Acid 15%)

Dermatica Custom Formula (Adapalene 0.1%, Azelaic Acid 15%)

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Prescription with 2 ingredients that contains azelaic acid and retinoid

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What's inside

Ingredients List

Active Ingredients: Adapalene 0.1%, Azelaic Acid 15%
Inactive Ingredients:

Key Ingredients

Benefits

Concerns

Ingredients Explained

Adapalene is a third-generation topical retinoid and is best known for treating mild to moderate acne. It’s also commonly as for its brand name, Differin.

Adapalene has some great benefits:

You can buy over-the-counter adapalene at 0.1% gel strength. Higher concentrations require a prescription.

Oleyl adapalenate is a cosmetic-grade derivative of adapalene that does not require a prescription since it is considered a cosmetic ingredient.

Learn more about Adapalene
Buffering, Masking

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Learn more about Azelaic Acid

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Where it's from

Dermatica is a British brand

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· Updated August 14, 2025 Added by rehaylew