Overview
What it is
Serum with 9 ingredients
Cool Features
It is reef safe
Suited For
It has ingredients that are good for dry skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Careness is from Japan. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Benefits
Ingredients Explained
Human Adipocyte Conditioned Media Extract (ADSC-CM) comes from the nutrient-rich media used to culture human fat-derived stem cells. It contains a blend of growth factors, enzymes, structural proteins, and cytokines (signaling proteins).
According to a manufacturer, this blend helps support:
One study found ADSC-CM to have anti-inflammatory properties that helped reduce redness, swelling, and encouraged tissue repair.
Besides skincare, this ingredient has been explored in medicine for its potential in wound healing, hair growth, and overall skin restoration.
Learn more about Human Adipocyte Conditioned Media ExtractWe don't have a description for Bacillus yet.
We don't have a description for Human Neonatal Fibroblast/Keratinocyte Conditioned Media yet.
This is a growth factor ingredient. Growth factors stimulate cell growth and healing.
Studies find they help with:
The term "conditioned media" refers to a mix of lab grown growth-factors. Just so you know - the US allows human-derived growth factors. However, human-derived growth factors are illegal in the EU and plant sources are used as an alternative.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
However, many people have seen great results from using growth factor serums.
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer.
Learn more about Human Neonatal Fibroblast Conditioned MediaSaccharomyces/Rice Lees Ferment Filtrate isn't fungal acne safe.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
This is a botanical extract from the rosemary plant (the same one you cook with). In skincare, it mostly works as a skin conditioning agent.
Its activity comes from a handful of polyphenols, carnosic acid, carnosol, and rosmarinic acid. Almost 90% of the antioxidant activity of this ingredient can be attributed to canosol and carnosic acid.
These compounds protect your skin two ways:
1) They fight off free radicals, or the unstable molecules from things like sun and pollution that age and damage skin.
2) They help calm inflammation by switching off the chemical signals that tell skin to get red and irritated.
Lab studies also suggest that rosmarinic acid may help protect collagen and slow sugar-related damage to it.
The Cosmetic Ingredient Review has concluded rosemary-derived ingredients to be safe when formulated to be non-sensitizing.
Rosemary can occasionally cause allergic contact dermatitis (due to carnosol), so be sure to patch test if you have reactive or fragrance-sensitive skin.
Learn more about Rosmarinus Officinalis Leaf ExtractGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
Careness is a Japanese brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published July 17, 2025 • Added by BlackCat808
