Careness Premium Serum

Careness Premium Serum

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Overview

What it is

Serum with 9 ingredients

Cool Features

It is reef safe

Suited For

It has ingredients that are good for dry skin and scar healing

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Careness is from Japan. This product is used in 2 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

Ingredients Explained

Human Adipocyte Conditioned Media Extract (ADSC-CM) comes from the nutrient-rich media used to culture human fat-derived stem cells. It contains a blend of growth factors, enzymes, structural proteins, and cytokines (signaling proteins).

According to a manufacturer, this blend helps support:

One study found ADSC-CM to have anti-inflammatory properties that helped reduce redness, swelling, and encouraged tissue repair.

Besides skincare, this ingredient has been explored in medicine for its potential in wound healing, hair growth, and overall skin restoration.

Learn more about Human Adipocyte Conditioned Media Extract
Skin Conditioning

We don't have a description for Bacillus yet.

We don't have a description for Human Neonatal Fibroblast/Keratinocyte Conditioned Media yet.

This is a growth factor ingredient. Growth factors stimulate cell growth and healing.

Studies find they help with:

The term "conditioned media" refers to a mix of lab grown growth-factors. Just so you know - the US allows human-derived growth factors. However, human-derived growth factors are illegal in the EU and plant sources are used as an alternative.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

However, many people have seen great results from using growth factor serums.

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer.

Learn more about Human Neonatal Fibroblast Conditioned Media
Emollient, Skin Conditioning

Saccharomyces/Rice Lees Ferment Filtrate isn't fungal acne safe.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Antimicrobial, Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.

Rosemary Leaf Extract contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid, a compound found in rosemary leaf, has been found to help soothe skin conditions such as eczema and acne.

Learn more about Rosmarinus Officinalis Leaf Extract
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water

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Where it's from

Careness is a Japanese brand

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Verified by SkinSort

We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.

The data we've presented on this page has been verified by a member of the SkinSort Team.

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· Published July 17, 2025 Added by BlackCat808