Back to Explore | Serums / Non Comedogenic From American Brands

Best Non Comedogenic American Serums

Explore the top non comedogenic serums from American brands with detailed ingredient breakdowns, usage guidelines, and reviews from skincare lovers like you.

About Comedogenic Ratings

"Non-Comedogenic" is a imperfect metric, and results can vary greatly between individuals.

We provide this data to help you with your research, but we always recommend doing further investigation on a formulation to see if it is right for you.

Learn more about this filter & how to use comedogenic ratings

Top products

Good Molecules

Hyaluronic Acid Serum

4.6 (21) ⸱ Serum ⸱ American

⸱ $12.00

vegan and cruelty-free serum that contains hyaluronic acid and vitamin e.

Details

This product contains 9 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin and scar healing
it is fungal acne (malassezia) safe and reef safe

Good Molecules

Niacinamide Serum

4.7 (20) ⸱ Serum ⸱ American

⸱ $12.00

vegan and cruelty-free serum that contains niacinamide.

Details

This product contains 9 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin, brightening skin, sensitive skin, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

Glow Recipe

Watermelon Glow Niacinamide Dew Drops

3.7 (20) ⸱ Serum ⸱ American

⸱ $32.00

vegan and cruelty-free serum that contains hyaluronic acid and niacinamide.

Details

This product contains 23 ingredients.

it doesn't contain any harsh alcohols, parabens, silicones or sulfates
it does contain common allergens, fragrances and oils
it is likely to be good for dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Timeless Skin Care

20% Vitamin C + E Ferulic Acid Serum

4.2 (6) ⸱ Serum ⸱ American

⸱ $22.31

cruelty-free serum that contains hyaluronic acid, vitamin c and vitamin e.

Details

This product contains 11 ingredients.

it doesn't contain any oils, parabens, silicones or sulfates
it does contain harsh alcohols, common allergens and fragrances
it is likely to be good for anti aging, dry skin, scar healing and dark spots
it is reef safe
it is not fungal acne (malassezia) safe

Naturium

Azelaic Topical Acid 10%

4.5 (4) ⸱ Serum ⸱ American

⸱ $19.99

vegan and cruelty-free serum that contains hyaluronic acid, niacinamide, vitamin c and vitamin e.

Details

This product contains 18 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

Naturium

Vitamin C Complex Serum

3.5 (2) ⸱ Serum ⸱ American

⸱ $19.99

vegan and cruelty-free serum that contains hyaluronic acid, vitamin c and vitamin e.

Details

This product contains 35 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
it is reef safe
it is not fungal acne (malassezia) safe

Drunk Elephant

B-Hydra Intensive Hydration Serum

3.1 (7) ⸱ Serum ⸱ American

⸱ $38.49

vegan and cruelty-free serum that contains hyaluronic acid and niacinamide.

Details

This product contains 28 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for dry skin, brightening skin, sensitive skin, scar healing and dark spots
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

Mad Hippie

Vitamin C Serum

4.2 (13) ⸱ Serum ⸱ American

⸱ $33.99

vegan and cruelty-free serum that contains exfoliants, hyaluronic acid and vitamin c.

Details

This product contains 17 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
it is fungal acne (malassezia) safe, reef safe and reef safe

Naturium

Niacinamide Serum 12% Plus Zinc 2%

2.7 (3) ⸱ Serum ⸱ American

⸱ $13.65

vegan and cruelty-free serum that contains hyaluronic acid, niacinamide and vitamin e.

Details

This product contains 16 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
it does contain silicones
it is likely to be good for fighting acne, dry skin, brightening skin, oily skin and scar healing
it is fungal acne (malassezia) safe and reef safe

Good Molecules

Super Peptide Serum

4.3 (3) ⸱ Serum ⸱ American

⸱ $12.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 15 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin and scar healing
it is fungal acne (malassezia) safe and reef safe

Good Molecules

Daily Brightening Serum

4.1 (9) ⸱ Serum ⸱ American

⸱ $8.00

cruelty-free serum that contains hyaluronic acid and vitamin e.

Details

This product contains 12 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

TruSkin

Vitamin C Face Serum with Hyaluronic Acid & Vitamin E

5.0 (2) ⸱ Serum ⸱ American

⸱ $21.97

vegan and cruelty-free serum that contains vitamin c and vitamin e.

Details

This product contains 18 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Glow Recipe

Plum Plump Hyaluronic Acid Serum

4.0 (2) ⸱ Serum ⸱ American

⸱ $45.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 35 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for dry skin
it is reef safe
it is not fungal acne (malassezia) safe

Aveeno

Calm + Restore Triple Oat Serum For Sensitive Skin

3.8 (8) ⸱ Serum ⸱ American

⸱ $14.43

serum that contains exfoliants.

Details

This product contains 19 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
it does contain oils and silicones
it is likely to be good for dry skin and sensitive skin
it is reef safe
it is not fungal acne (malassezia) safe

Sunday Riley

C.E.O. 15% Vitamin C Brightening Serum

5.0 (1) ⸱ Serum ⸱ American

⸱ $43.00

cruelty-free serum that contains aha, vitamin c and vitamin e.

Details

This product contains 22 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for anti aging, dry skin, brightening skin, reducing pores, scar healing and better texture
it is reef safe
it is not fungal acne (malassezia) safe

Glow Recipe

Strawberry Smooth BHA + AHA Salicylic Acid Serum

3.9 (8) ⸱ Serum ⸱ American

⸱ $42.00

vegan and cruelty-free serum that contains aha, bha, hyaluronic acid and niacinamide.

Details

This product contains 36 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
it is reef safe
it is not fungal acne (malassezia) safe

Drunk Elephant

T.L.C. Framboos Glycolic Night Serum

2.5 (4) ⸱ Serum ⸱ American

⸱ $37.99

vegan and cruelty-free serum that contains aha, bha and hyaluronic acid.

Details

This product contains 36 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

Prequel

Multi-Quench Plumping Hydration Serum

5.0 (3) ⸱ Serum ⸱ American

vegan and cruelty-free serum that contains vitamin e.

Details

This product contains 18 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin and scar healing
it is fungal acne (malassezia) safe and reef safe

Cocokind

Vitamin C Glow Serum

4.5 (4) ⸱ Serum ⸱ American

⸱ $16.99

vegan and cruelty-free serum that contains hyaluronic acid and vitamin c.

Details

This product contains 19 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
it is fungal acne (malassezia) safe and reef safe

Naturium

Tranexamic Topical Acid 5%

3.5 (2) ⸱ Serum ⸱ American

⸱ $19.99

vegan and cruelty-free serum that contains aha, hyaluronic acid, niacinamide and vitamin e.

Details

This product contains 22 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

Prequel

Lucent-C Brightening Vitamin C Serum

3.4 (9) ⸱ Serum ⸱ American

vegan and cruelty-free serum that contains niacinamide and vitamin c.

Details

This product contains 14 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

DRMTLGY

Needle-Less Serum

4.7 (3) ⸱ Serum ⸱ American

cruelty-free serum that contains ceramides, hyaluronic acid, niacinamide, peptides and vitamin e.

Details

This product contains 29 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or silicones
it does contain sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Biossance Squalane + Copper Peptide Rapid Plumping Serum Original

Biossance
2 Types
Squalane + Copper Peptide Rapid Plumping Serum

3.8 (5) ⸱ Serum ⸱ American

⸱ $68.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 32 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for anti aging, dry skin, sensitive skin, scar healing and dark spots
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

Timeless Skin Care

CoEnzyme Q10 Serum

4.0 (2) ⸱ Serum ⸱ American

⸱ $11.54

cruelty-free serum that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 13 ingredients.

it doesn't contain any oils, parabens, silicones or sulfates
it does contain harsh alcohols, common allergens and fragrances
it is likely to be good for anti aging, dry skin, brightening skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Neutrogena Hydro Boost Hyaluronic Acid Serum US

Neutrogena
2 Regions
Hydro Boost Hyaluronic Acid Serum

3.0 (2) ⸱ Serum ⸱ American

⸱ $19.97

serum that contains hyaluronic acid.

Details

This product contains 23 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin, brightening skin and scar healing
it is not fungal acne (malassezia) safe

Glossier

Super Pure Clarifying Face Serum with Niacinamide + Zinc

3.0 (4) ⸱ Serum ⸱ American

⸱ $29.00

vegan and cruelty-free serum that contains niacinamide.

Details

This product contains 13 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Glow Recipe

Guava Vitamin C Dark Spot Treatment Serum

4.0 (6) ⸱ Serum ⸱ American

⸱ $45.00

vegan and cruelty-free serum that contains hyaluronic acid, peptides, vitamin c and vitamin e.

Details

This product contains 47 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
it is reef safe
it is not fungal acne (malassezia) safe

Timeless Skin Care

10% Vitamin C + E Ferulic Acid Serum

3.0 (2) ⸱ Serum ⸱ American

⸱ $18.39

cruelty-free serum that contains hyaluronic acid, vitamin c and vitamin e.

Details

This product contains 11 ingredients.

it doesn't contain any oils, parabens, silicones or sulfates
it does contain harsh alcohols, common allergens and fragrances
it is likely to be good for anti aging, dry skin, scar healing and dark spots
it is reef safe
it is not fungal acne (malassezia) safe

SkinCeuticals

Hyaluronic Acid Intensifier (H.A.)

5.0 (5) ⸱ Serum ⸱ American

⸱ $110.00

serum that contains exfoliants, hyaluronic acid and vitamin e.

Details

This product contains 35 ingredients.

it doesn't contain any parabens or sulfates
it does contain harsh alcohols, common allergens, fragrances, oils and silicones
it is likely to be good for anti aging, dry skin, sensitive skin, reducing pores, scar healing and dark spots
it is reef safe
it is not fungal acne (malassezia) safe

Hero Cosmetics

Lightning Wand Dark Spot Brightening Serum

2.8 (5) ⸱ Serum ⸱ American

⸱ $19.99

cruelty-free serum that contains aha, hyaluronic acid, niacinamide and vitamin c.

Details

This product contains 35 ingredients.

it doesn't contain any common allergens, oils, parabens, silicones or sulfates
it does contain harsh alcohols and fragrances
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
it is fungal acne (malassezia) safe and reef safe