Overview
What it is
Serum with 3 ingredients that contains hyaluronic acid
Cool Features
It is cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Majestic Cosme is from Japan.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
Warning: Incomplete INCI list
This happens when the brand does not publicly disclose the full list of ingredients.
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Ingredients List
Human Stem Cell Conditioned Media 20%
Hyaluronic Acid
Humectant
Collagen
Moisturising
Active Ingredients:
Human Stem Cell Conditioned Media 20%
Inactive Ingredients:
Hyaluronic Acid, Collagen
Key Ingredients
Benefits
Ingredients Explained
This ingredient is a nutrient liquid collected after human cells are grown in culture. It usually contains a mix of signaling proteins, peptides, and other vesicles that cells release.
The compounds in this ingredient can theoretically support healthier skin. One clinical study of a cosmetic containing this ingredient reported improvements in hydration and wrinkle depth.
However, high quality human topical data is still limited for this ingredient at this time.
Learn more about Human Stem Cell Conditioned MediaHyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidCollagen is a big structural protein that your body uses to keep skin firm and bouncy. Despite the marketing, topically applied collagen doesn't "refill" the collagen in your skin.
The molecule is too big to pass through your skin barrier so intact Collagen physically can't get past the surface.
What it actually does in your skincare is work as a humectant and film-former: it binds water, lays down a light moisturizing film, and reduces water loss from the surface. This helps make skin feel smoother and temporarily plumper.
This ingredient has been found safe for use in cosmetics with clinical studies showing no irritation, sensitization, or phototoxicity. It's typically used at low concentrations (often a fraction of a percent up to a few percent).
Collagen will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about hydrolyzed collagen or soluble collagen.
Learn more about CollagenReviews
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Where it's from
Majestic Cosme is a Japanese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated February 6, 2026 • Added by AgelessOptimized
