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Best American Skincare Products with Peptides

Explore the top products with peptides from American brands with detailed ingredient breakdowns, usage guidelines, and reviews from skincare lovers like you.

Top products

Good Molecules

Yerba Mate Wake Up Eye Gel

4.1 (9) ⸱ Eye Moisturizer ⸱ American

⸱ $6.00

vegan and cruelty-free eye moisturizer that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 22 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Clinique

Moisture Surge™ 100-Hour Auto-Replenishing Hydrator

4.2 (19) ⸱ Moisturizer ⸱ American

⸱ $29.00

general moisturizer that contains hyaluronic acid, peptides, vitamin c and vitamin e.

Details

This product contains 43 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens or sulfates
it does contain fragrances and silicones
it is likely to be good for dry skin, brightening skin, sensitive skin and reducing pores
it is reef safe
it is not fungal acne (malassezia) safe

CeraVe

Skin Renewing Night Cream to Soften Skin

3.5 (11) ⸱ Night Moisturizer ⸱ American

⸱ $15.38

night moisturizer that contains ceramides, hyaluronic acid, niacinamide, peptides and vitamin e.

Details

This product contains 40 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils or parabens
it does contain silicones and sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Estée Lauder

Advanced Night Repair Synchronized Multi-Recovery Complex Serum

4.7 (9) ⸱ Serum ⸱ American

⸱ $59.99

serum that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 43 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for dry skin
it is reef safe
it is not fungal acne (malassezia) safe

Drunk Elephant Protini Polypeptide Cream US

Drunk Elephant
3 Regions
Protini Polypeptide Cream

3.7 (18) ⸱ Moisturizer ⸱ American

⸱ $68.00

vegan and cruelty-free general moisturizer that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 58 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for anti aging, dry skin and scar healing
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

e.l.f. cosmetics

Holy Hydration! Makeup Melting Cleansing Balm

3.3 (14) ⸱ Makeup Remover ⸱ American

⸱ $11.00

vegan and cruelty-free makeup remover that contains ceramides, exfoliants and peptides.

Details

This product contains 29 ingredients.

it doesn't contain any harsh alcohols, parabens, silicones or sulfates
it does contain common allergens, fragrances and oils
it is likely to be good for anti aging, dry skin and sensitive skin
it is reef safe
it is not fungal acne (malassezia) safe

e.l.f. cosmetics Holy Hydration! Face Cream US

e.l.f. cosmetics
2 Regions
Holy Hydration! Face Cream

2.8 (8) ⸱ Moisturizer ⸱ American

⸱ $12.00

vegan and cruelty-free general moisturizer that contains exfoliants, hyaluronic acid, niacinamide and peptides.

Details

This product contains 32 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
it does contain silicones
it is likely to be good for anti aging, dry skin, brightening skin and sensitive skin
it is reef safe
it is not fungal acne (malassezia) safe

Paula's Choice
2 Regions
1% Retinol Treatment

4.5 (4) ⸱ Facial Treatment ⸱ American

⸱ $62.00

vegan and cruelty-free facial treatment that contains ceramides, exfoliants, hyaluronic acid, peptides, retinoid, vitamin c and vitamin e.

Details

This product contains 53 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
it does contain oils and silicones
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
it is reef safe
it is not fungal acne (malassezia) safe

Good Molecules

Super Peptide Serum

4.3 (3) ⸱ Serum ⸱ American

⸱ $12.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 15 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging and dry skin
it is fungal acne (malassezia) safe and reef safe

Biossance

Squalane + Marine Algae Eye Cream

3.9 (7) ⸱ Eye Moisturizer ⸱ American

⸱ $56.00

vegan and cruelty-free eye moisturizer that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 21 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging and dry skin
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

Glow Recipe

Plum Plump Hyaluronic Acid Serum

4.0 (1) ⸱ Serum ⸱ American

⸱ $45.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 35 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for dry skin
it is reef safe
it is not fungal acne (malassezia) safe

Authentic Ego

Super Sensa Barrier Repair Moisturizer With Pre & Postbiotics

4.3 (18) ⸱ Moisturizer ⸱ American

vegan and cruelty-free general moisturizer that contains niacinamide, peptides and vitamin e.

Details

This product contains 27 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for dry skin, sensitive skin, scar healing and dark spots
it is fungal acne (malassezia) safe and reef safe

Clinique

Moisture Surge Intense 72H Lipid-Replenishing Hydrator Moisturizer

5.0 (1) ⸱ Moisturizer ⸱ American

⸱ $29.00

general moisturizer that contains exfoliants, hyaluronic acid, peptides and vitamin e.

Details

This product contains 39 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
it does contain oils and silicones
it is likely to be good for dry skin
it is reef safe
it is not fungal acne (malassezia) safe

Estée Lauder

Advanced Night Repair Eye Supercharged Complex

3.3 (4) ⸱ Eye Moisturizer ⸱ American

⸱ $26.99

eye moisturizer that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 48 ingredients.

it doesn't contain any harsh alcohols, common allergens or parabens
it does contain fragrances, oils, silicones and sulfates
it is likely to be good for dry skin
it is reef safe
it is not fungal acne (malassezia) safe

Olay

Regenerist Retinol 24 Night Facial Moisturizer

4.0 (2) ⸱ Night Moisturizer ⸱ American

⸱ $29.94

night moisturizer that contains niacinamide, peptides, retinoid and spf.

Details

This product contains 24 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
it does contain silicones
it is likely to be good for fighting acne, anti aging, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
it is not fungal acne (malassezia) safe

Naturium

Multi-Peptide Advanced Serum

4.3 (4) ⸱ Serum ⸱ American

vegan and cruelty-free serum that contains exfoliants, peptides and vitamin e.

Details

This product contains 47 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens or sulfates
it does contain fragrances and silicones
it is likely to be good for anti aging, dry skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Dieux Skin

Instant Angel

3.4 (5) ⸱ Moisturizer ⸱ American

vegan and cruelty-free general moisturizer that contains aha, ceramides, hyaluronic acid, peptides and vitamin e.

Details

This product contains 43 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for anti aging, dry skin, brightening skin, scar healing and better texture
it is reef safe
it is not fungal acne (malassezia) safe

Kiehl's

Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide

4.8 (4) ⸱ Serum ⸱ American

⸱ $65.00

serum that contains ceramides, hyaluronic acid, niacinamide, peptides, retinoid and vitamin e.

Details

This product contains 43 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
it is reef safe
it is not fungal acne (malassezia) safe

DRMTLGY

Needle-Less Serum

4.7 (3) ⸱ Serum ⸱ American

cruelty-free serum that contains ceramides, hyaluronic acid, niacinamide, peptides and vitamin e.

Details

This product contains 29 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or silicones
it does contain sulfates
it is likely to be good for anti aging, dry skin, brightening skin and sensitive skin
it is reef safe
it is not fungal acne (malassezia) safe

Estée Lauder

Advanced Night Repair Synchronized Recovery Complex II

5.0 (6) ⸱ Serum ⸱ American

⸱ $41.89

serum that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 40 ingredients.

it doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
it does contain fragrances and oils
it is likely to be good for dry skin
it is not fungal acne (malassezia) safe

Glow Recipe

Avocado Ceramide Recovery Serum

4.5 (2) ⸱ Serum ⸱ American

⸱ $45.00

vegan and cruelty-free serum that contains ceramides, niacinamide, peptides, vitamin c and vitamin e.

Details

This product contains 66 ingredients.

it doesn't contain any harsh alcohols, parabens, silicones or sulfates
it does contain common allergens, fragrances and oils
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Naturium

Multi-Peptide Moisturizer

1.5 (2) ⸱ Moisturizer ⸱ American

⸱ $19.99

vegan and cruelty-free general moisturizer that contains hyaluronic acid, niacinamide, peptides, vitamin c and vitamin e.

Details

This product contains 48 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
it does contain oils and silicones
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and reducing pores
it is reef safe
it is not fungal acne (malassezia) safe

Summer Fridays

Cloud Dew Oil-Free Gel Cream Moisturizer

4.7 (3) ⸱ Moisturizer ⸱ American

⸱ $45.00

vegan and cruelty-free general moisturizer that contains ceramides, hyaluronic acid, peptides, vitamin c and vitamin e.

Details

This product contains 52 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

CeraVe

Skin Renewing Eye Cream

3.0 (1) ⸱ Eye Moisturizer ⸱ American

⸱ $17.03

eye moisturizer that contains ceramides, hyaluronic acid, niacinamide and peptides.

Details

This product contains 33 ingredients.

it doesn't contain any harsh alcohols, common allergens or parabens
it does contain fragrances, oils, silicones and sulfates
it is likely to be good for anti aging, dry skin, brightening skin and sensitive skin
it is reef safe
it is not fungal acne (malassezia) safe

Biossance Squalane + Copper Peptide Rapid Plumping Serum Original

Biossance
2 Types
Squalane + Copper Peptide Rapid Plumping Serum

3.8 (5) ⸱ Serum ⸱ American

⸱ $68.00

vegan and cruelty-free serum that contains hyaluronic acid and peptides.

Details

This product contains 32 ingredients.

it doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
it does contain fragrances
it is likely to be good for anti aging, dry skin and sensitive skin
it is reef safe and reef safe
it is not fungal acne (malassezia) safe

Timeless Skin Care

CoEnzyme Q10 Serum

4.0 (2) ⸱ Serum ⸱ American

⸱ $11.54

cruelty-free serum that contains hyaluronic acid, peptides and vitamin e.

Details

This product contains 13 ingredients.

it doesn't contain any oils, parabens, silicones or sulfates
it does contain harsh alcohols, common allergens and fragrances
it is likely to be good for anti aging, dry skin, brightening skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Paula's Choice

Clear Oil-Free Moisturizer

2.8 (4) ⸱ Moisturizer ⸱ American

⸱ $29.00

cruelty-free general moisturizer that contains ceramides, hyaluronic acid, niacinamide and peptides.

Details

This product contains 35 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

rhode

Barrier Restore Cream

4.7 (3) ⸱ Moisturizer ⸱ American

vegan and cruelty-free general moisturizer that contains hyaluronic acid, niacinamide, peptides and vitamin e.

Details

This product contains 35 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
it is likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
it is reef safe
it is not fungal acne (malassezia) safe

Glow Recipe

Guava Vitamin C Dark Spot Treatment Serum

4.0 (6) ⸱ Serum ⸱ American

⸱ $45.00

vegan and cruelty-free serum that contains hyaluronic acid, peptides, vitamin c and vitamin e.

Details

This product contains 47 ingredients.

it doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
it does contain oils
it is likely to be good for anti aging, dry skin, brightening skin, reducing pores, scar healing, dark spots and better texture
it is reef safe
it is not fungal acne (malassezia) safe

ZO Skin Health

Daily Power Defense

Day Moisturizer ⸱ American

day moisturizer that contains peptides, retinoid and vitamin e.

Details

This product contains 51 ingredients.

it doesn't contain any harsh alcohols or sulfates
it does contain common allergens, fragrances, oils, parabens and silicones
it is likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
it is not fungal acne (malassezia) safe