Welcome to our breakdown of the 16 best Polysporin Original Antibiotic Cream dupes and alternatives.
Looking for dupes for a different product? You can use our Dupe Finder to search for them!
If you'd like to see the all of the Polysporin dupes that we've found, check out our best Polysporin dupes guide.
We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology
Our Roundup
Here's a quick roundup of our findings. Continue reading for the full breakdown!
CVS Health's Zinc Oxide Ointment is the dupe with the most similar ingredients. Our matching methodology puts it at an 46% ingredient match!
Of all of the dupes for this product, Differin's Adapalene Gel 0.1% Acne Treatment is the most liked by our community. Our matching algorithm puts it at an 57% overall match!
- CVS Health Zinc Oxide Ointment 1
- Gladskin Rosacear Cream 2
- Perrigo Hydroquinone 4% Cream 3
- MCoBeauty. Miracle Xtreme Pimple Patches 4
- Cimed Acnezil Gel Peróxido de Benzoíla 5% 5
- Tout Vert HR-Z 6
- Viva Cosmetics Whitening Cream 7
- Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution 8
- Glenmark Pharma Adapalene + Clindamycin Phosphate gel 9
- Neutrogena 0.1% Adapalene Gel Acne Treatment 10
- La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne 11
- Walgreens 0.1% Adapalene Treatment Gel Fragrance Free 12
- Panoxyl Adapalene 0.1% Leave-On Gel 13
- Differin Adapalene Gel 0.1% Acne Treatment 14
- DMD Skin Sciences Mission: Skin Acnoregulin Spray 15
- CVS Health Adapalene Gel USP 0.1% Acne Treatment 16
Overview
What it is
Facial treatment with 7 ingredients
Suited For
It has ingredients that are good for dry skin
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, silicones or sulfates
Polysporin Original Antibiotic Cream
66% match
with the ingredients and function of CVS Health Zinc Oxide Ointment
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
63% match
with the ingredients and function of Gladskin Rosacear Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Perrigo Hydroquinone 4% Cream
61% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
MCoBeauty. Miracle Xtreme Pimple Patches
61% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates. They both contain oils.
They're both likely to be good for dry skin.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
61% match
with the ingredients and function of Cimed Acnezil Gel Peróxido de Benzoíla 5%
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances or silicones. They both contain oils and parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Tout Vert HR-Z
61% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
59% match
with the ingredients and function of Viva Cosmetics Whitening Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 5 ingredients in common.
They both do not contain any harsh alcohols, common allergens or sulfates. They both contain oils and parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution
58% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Glenmark Pharma Adapalene + Clindamycin Phosphate gel
58% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 4 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates. They both contain parabens.
They're both likely to be good for dry skin.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Neutrogena 0.1% Adapalene Gel Acne Treatment
58% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne
57% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Walgreens 0.1% Adapalene Treatment Gel Fragrance Free
57% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Panoxyl Adapalene 0.1% Leave-On Gel
57% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
57% match
with the ingredients and function of Differin Adapalene Gel 0.1% Acne Treatment
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
DMD Skin Sciences Mission: Skin Acnoregulin Spray
56% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any common allergens, fragrances, oils or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
CVS Health Adapalene Gel USP 0.1% Acne Treatment
55% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates. They both contain parabens.
They're both likely to be good for dry skin.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
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The data we've presented on this page has been verified by a member of the SkinSort Team.
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