Welcome to our breakdown of the 11 best Polysporin Original Antibiotic Cream dupes and alternatives.
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If you'd like to see the all of the Polysporin dupes that we've found, check out our best Polysporin dupes guide.
We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology
Our Roundup
Here's a quick roundup of our findings. Continue reading for the full breakdown!
CVS Health's Zinc Oxide Ointment is the dupe with the most similar ingredients. Our matching methodology puts it at an 46% ingredient match!
Of all of the dupes for this product, Differin's Adapalene Gel 0.1% Acne Treatment is the most liked by our community. Our matching algorithm puts it at an 57% overall match!
- CVS Health Zinc Oxide Ointment 1
- Bausch Health Arazlo Tazarotene Lotion, 0.045% 2
- Gladskin Rosacear Cream 3
- Perrigo Hydroquinone 4% Cream 4
- Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution 5
- Neutrogena 0.1% Adapalene Gel Acne Treatment 6
- Differin Adapalene Gel 0.1% Acne Treatment 7
- La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne 8
- Walgreens 0.1% Adapalene Treatment Gel Fragrance Free 9
- Panoxyl Adapalene 0.1% Leave-On Gel 10
- DMD Skin Sciences Mission: Skin Acnoregulin Spray 11
Overview
What it is
Facial treatment with 7 ingredients
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, silicones or sulfates
Polysporin Original Antibiotic Cream
66% match
with the ingredients and function of CVS Health Zinc Oxide Ointment
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
64% match
with the ingredients and function of Bausch Health Arazlo Tazarotene Lotion, 0.045%
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Gladskin Rosacear Cream
63% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
61% match
with the ingredients and function of Perrigo Hydroquinone 4% Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
58% match
with the ingredients and function of Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any common allergens, fragrances, oils, silicones or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Neutrogena 0.1% Adapalene Gel Acne Treatment
58% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Differin Adapalene Gel 0.1% Acne Treatment
57% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
57% match
with the ingredients and function of La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Walgreens 0.1% Adapalene Treatment Gel Fragrance Free
57% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Polysporin Original Antibiotic Cream
57% match
with the ingredients and function of Panoxyl Adapalene 0.1% Leave-On Gel
Dupe Explained
These products are both facial treatments that contain. They've got a total of 3 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
DMD Skin Sciences Mission: Skin Acnoregulin Spray
56% match
with the ingredients and function of Polysporin Original Antibiotic Cream
Dupe Explained
These products are both facial treatments that contain. They've got a total of 2 ingredients in common.
They both do not contain any common allergens, fragrances, oils or sulfates.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
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The data we've presented on this page has been verified by a member of the SkinSort Team.
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