Differin Adapalen 0.1% Gel

Dupes for Adapalen 0.1% Gel by Differin

Last updated on July 05, 2025

Welcome to our breakdown of the 27 best Differin Adapalen 0.1% Gel dupes and alternatives.

Looking for dupes for a different product? You can use our Dupe Finder to search for them!

If you'd like to see the all of the Differin dupes that we've found, check out our best Differin dupes guide.

We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology

Our Roundup

Here's a quick roundup of our findings. Continue reading for the full breakdown!

up&up Adapalene Gel 0.1%
Most Similar Ingredients

up&up's Adapalene Gel 0.1% is the dupe with the most similar ingredients. Our matching methodology puts it at an 78% ingredient match!

Differin Adapalene Gel 0.1% Acne Treatment
Most Liked

Of all of the dupes for this product, Differin's Adapalene Gel 0.1% Acne Treatment is the most liked by our community. Our matching algorithm puts it at an 79% overall match!

Overview

What it is

Facial treatment with 9 ingredients that contains retinoid

Cool Features

It is fungal acne (malassezia) safe and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Dupe #4

up&up Adapalene Gel 0.1%

87% match

with the ingredients and function of Differin Adapalen 0.1% Gel

100% Attribute Match
78% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Taro Adapalene Gel 0.1%

87% match

with the ingredients and function of Differin Adapalen 0.1% Gel

100% Attribute Match
78% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne

79% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #4

Panoxyl Adapalene 0.1% Leave-On Gel

79% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Differin Adapalene Gel 0.1% Acne Treatment

79% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Walgreens 0.1% Adapalene Treatment Gel Fragrance Free

78% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Neutrogena 0.1% Adapalene Gel Acne Treatment

78% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #8

Glenmark Pharma Adapalene Gel USP, 0.1%

78% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
63% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Don't miss the latest dupes
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Dupe #3

CVS Health Adapalene Gel USP 0.1% Acne Treatment

78% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
62% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #10

Proactiv Adapalene Gel 0.1% Acne Treatment

76% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
60% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #11

Acne Free Adapalene Gel 0.1%

76% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
60% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #12

Glenmark Pharma Klenzit-C Adapalene + Clindamycin Phosphate Gel

75% match

with the ingredients and function of Differin Adapalen 0.1% Gel

96% Attribute Match
58% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #4

Ichthyol Cordes BPO

64% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #5

Deriva MS Aqueous Gel

63% match

with the ingredients and function of Differin Adapalen 0.1% Gel

100% Attribute Match
40% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 2 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, oily skin, reducing pores, scar healing and better texture.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #15

T3 Adapalene Gel 0.1%

62% match

with the ingredients and function of Differin Adapalen 0.1% Gel

78% Attribute Match
42% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

They're both likely to be good for fighting acne and anti aging.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Don't miss the latest dupes
Build your routine, discover dupes, and more by joining our community
Dupe #3

Face Reality Skincare 5% Acne Med

61% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #5

Acnecide Face Gel Spot Treatment with Benzoyl Peroxide

60% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #18

Benzac AC Moderate Strength 5% Acne Gel

60% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #6

Dr. Song 2.5% Benzoyl Peroxide Advanced Acne Gel

60% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #4

Perrigo Adapalene Cream, 0.1%

60% match

with the ingredients and function of Differin Adapalen 0.1% Gel

78% Attribute Match
37% Ingredient Match

Dupe Explained

These products are both facial treatments that contain retinoid. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils or sulfates.

They're both likely to be good for fighting acne and anti aging.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #7

Hasco-lek Hascoderm Lipogel

59% match

with the ingredients and function of Differin Adapalen 0.1% Gel

58% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #7

acne.org Treatment (Benzoyl Peroxide – 2.5%)

59% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
39% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #23

Apoteket Punktbehandling

57% match

with the ingredients and function of Differin Adapalen 0.1% Gel

63% Attribute Match
39% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any oils, parabens, silicones or sulfates.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #6

Touch Acne Treatment Gel Benzoyl Peroxide 2.5%

57% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
36% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #25

Botica Sérum de Ácido Azelaico

55% match

with the ingredients and function of Differin Adapalen 0.1% Gel

65% Attribute Match
36% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #8

Botica Sérum de Ácido Tranexùmico

55% match

with the ingredients and function of Differin Adapalen 0.1% Gel

65% Attribute Match
36% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #27

COLLISTAR Milano Hyaluronic Acid Molecular Spray

55% match

with the ingredients and function of Differin Adapalen 0.1% Gel

75% Attribute Match
36% Ingredient Match

Dupe Explained

These products are both facial treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for anti aging.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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