Welcome to our breakdown of the 47 best Cetaphil Advanced Defense Serum dupes and alternatives.
Looking for dupes for a different product? You can use our Dupe Finder to search for them!
If you'd like to see the all of the Cetaphil dupes that we've found, check out our best Cetaphil dupes guide.
We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology
Our Roundup
Here's a quick roundup of our findings. Continue reading for the full breakdown!
COSRX's The Niacinamide 15 Serum is the dupe with the most similar ingredients. Our matching methodology puts it at an 53% ingredient match!
Of all of the dupes for this product, COSRX's The Niacinamide 15 Serum is the most liked by our community. Our matching algorithm puts it at an 71% overall match!
- COSRX The Niacinamide 15 Serum 1
- Endota Organics Strengthening B Serum 2
- Tulus Pore-Fecting Niacinamide Serum 3
- Soul Apothecary Niacinamide + HA Serum in 10% 4
- GoodnDoc Hydra B5 Serum 5
- Herbario Butterfly Pea Boosted Serum 6
- Hyaloo White Truffle Serum Spray 7
- Mizon Hyalugen Le Lift Serum 8
- KoeRX Gorjes Magnificent Ace Serum 9
- Bioderma Hydrabio Hyalu+ Serum 10
- Dermatica Daily Hydration 5HA+Cica Serum 11
- Nevada Vitamin E + Alpha Arbutin Serum 12
- PURITO Pure Vitamin C Serum 13
- Merit Beauty Great Skin Instant Glow Serum 14
- Avène Hydrance Boost Concentrated Hydrating Serum 15
- Reyal Performance Serum [002] 16
- HALE Even Tone Potion 17
- Cute Press Calming Cica Booster Serum 18
- Ruruberry NPAA Serum 19
- Seonglow 15+ Niacinamide Vegan Serum 20
- feelxo: Glacier 5D Hyaluronic Serum 21
- Tia’m Pore Minimizing 21 Serum 22
- Skindoze Glow Get It! Brightening Serum 23
- Physician's Formula Skin Booster Vitamin Shot Hydrating 24
- Mary & May Hyaluronics Serum 25
- Oh K! Illuminating Serum 26
- Julioly Green Fig Smoothing Filter Serum 27
- Soul Apothecary Alpha Arbutin Plus Serum 28
- Jorgobé Niacinamide Serum 29
- Nano Recipe Niacinamide 20% Concentrate Serum 30
- Rael Miracle Clear Microcrystal Activated PM Serum 2000 31
- Colibri Skincare Niacinamide Booster 32
- Barle Soothing Barrier Serum 33
- Forganica Skincare Pore Tightening Serum 34
- Believe Beauty Hyaluronic Acid Serum 35
- Fuzed The Barrier Repair Serum 36
- Boots Ingredients Hyaluronic Acid Serum 2% 37
- IVY AÏA Blossom Face Serum With Hyaluronic Acid 38
- Cledbel Collagen Niacinamide Serum 39
- Dr.G 3X Panthenol Hyaluronic Acid Booster Serum 40
- iUNIK Rose Galactomyces Synergy Serum 41
- Avène Retrinal Advanced Correcting Serum 42
- Cute Press 1 Week Brightening Booster Serum 43
- Tia’m Vita B3 Source 44
- Avène Hyaluron Activ B3 Concentrated Plumping Serum 45
- Clay And Glow Niacinamide Treatment Serum 46
- Apoliva Advanced Niacinamid Serum 47
Overview
What it is
Serum with 16 ingredients that contains hyaluronic acid, niacinamide and Vitamin E
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Cetaphil Advanced Defense Serum
71% match
with the ingredients and function of COSRX The Niacinamide 15 Serum
Dupe Explained
These products are both serums that contain niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $2.34 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Endota Organics Strengthening B Serum
70% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cetaphil Advanced Defense Serum
70% match
with the ingredients and function of Tulus Pore-Fecting Niacinamide Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 10 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Soul Apothecary Niacinamide + HA Serum in 10%
70% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
GoodnDoc Hydra B5 Serum
69% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cetaphil Advanced Defense Serum
69% match
with the ingredients and function of Herbario Butterfly Pea Boosted Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Hyaloo White Truffle Serum Spray
68% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Mizon Hyalugen Le Lift Serum
68% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
This dupe is $2.16 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
KoeRX Gorjes Magnificent Ace Serum
68% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 9 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Bioderma Hydrabio Hyalu+ Serum
67% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Dermatica Daily Hydration 5HA+Cica Serum
67% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Nevada Vitamin E + Alpha Arbutin Serum
67% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cetaphil Advanced Defense Serum
67% match
with the ingredients and function of PURITO Pure Vitamin C Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
This dupe is $8.14 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Merit Beauty Great Skin Instant Glow Serum
67% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $0.84 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cetaphil Advanced Defense Serum
67% match
with the ingredients and function of Avène Hydrance Boost Concentrated Hydrating Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $22.15 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Reyal Performance Serum [002]
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
HALE Even Tone Potion
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cute Press Calming Cica Booster Serum
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Ruruberry NPAA Serum
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Seonglow 15+ Niacinamide Vegan Serum
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 10 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $0.86 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
feelxo: Glacier 5D Hyaluronic Serum
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Tia’m Pore Minimizing 21 Serum
66% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
This dupe is $7.94 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Skindoze Glow Get It! Brightening Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Physician's Formula Skin Booster Vitamin Shot Hydrating
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Price Comparison
This dupe is $9.44 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Mary & May Hyaluronics Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $7.51 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Oh K! Illuminating Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Julioly Green Fig Smoothing Filter Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Soul Apothecary Alpha Arbutin Plus Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Jorgobé Niacinamide Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Nano Recipe Niacinamide 20% Concentrate Serum
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain niacinamide. They've got a total of 4 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $3.92 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Rael Miracle Clear Microcrystal Activated PM Serum 2000
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $3.15 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Colibri Skincare Niacinamide Booster
65% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Barle Soothing Barrier Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Forganica Skincare Pore Tightening Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Believe Beauty Hyaluronic Acid Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Fuzed The Barrier Repair Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Boots Ingredients Hyaluronic Acid Serum 2%
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for dry skin, brightening skin, sensitive skin and scar healing.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
IVY AÏA Blossom Face Serum With Hyaluronic Acid
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cledbel Collagen Niacinamide Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $5.16 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Dr.G 3X Panthenol Hyaluronic Acid Booster Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
iUNIK Rose Galactomyces Synergy Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cetaphil Advanced Defense Serum
64% match
with the ingredients and function of Avène Retrinal Advanced Correcting Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also reef safe.
Price Comparison
This dupe is $58.16 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Cute Press 1 Week Brightening Booster Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $12.91 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Tia’m Vita B3 Source
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $9.44 less expensive than the original product. Nice find!
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Avène Hyaluron Activ B3 Concentrated Plumping Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 5 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Price Comparison
This dupe is $22.15 more expensive than the original product.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Clay And Glow Niacinamide Treatment Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
Apoliva Advanced Niacinamid Serum
64% match
with the ingredients and function of Cetaphil Advanced Defense Serum
Dupe Explained
These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.
Both products are also fungal acne (malassezia) safe and reef safe.
Learn more about this dupe
Looking for a full breakdown of the similarities and differences between these two products?
Check out our full comparison of these two products for all the details!
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The data we've presented on this page has been verified by a member of the SkinSort Team.
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