Cetaphil Advanced Defense Serum

Dupes for Advanced Defense Serum by Cetaphil

Last updated on March 24, 2026

Welcome to our breakdown of the 50 best Cetaphil Advanced Defense Serum dupes and alternatives.

Looking for dupes for a different product? You can use our Dupe Finder to search for them!

If you'd like to see the all of the Cetaphil dupes that we've found, check out our best Cetaphil dupes guide.

We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology

Our Roundup

Here's a quick roundup of our findings. Continue reading for the full breakdown!

COSRX The Niacinamide 15 Serum
Most Similar Ingredients

COSRX's The Niacinamide 15 Serum is the dupe with the most similar ingredients. Our matching methodology puts it at an 53% ingredient match!

COSRX The Niacinamide 15 Serum
Most Liked

Of all of the dupes for this product, COSRX's The Niacinamide 15 Serum is the most liked by our community. Our matching algorithm puts it at an 71% overall match!

Overview

What it is

Serum with 16 ingredients that contains hyaluronic acid, niacinamide and Vitamin E

Cool Features

It is fungal acne (malassezia) safe and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Dupe #1

COSRX The Niacinamide 15 Serum

71% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
53% Ingredient Match

Dupe Explained

These products are both serums that contain niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $2.34 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #18

Cetaphil Advanced Defense Serum

70% match

with the ingredients and function of Tulus Pore-Fecting Niacinamide Serum

98% Attribute Match
51% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 10 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Endota Organics Strengthening B Serum

70% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
54% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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Dupe #3

Soul Apothecary Niacinamide + HA Serum in 10%

70% match

with the ingredients and function of Cetaphil Advanced Defense Serum

100% Attribute Match
50% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Cetaphil Advanced Defense Serum

69% match

with the ingredients and function of Herbario Butterfly Pea Boosted Serum

92% Attribute Match
49% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Cetaphil Advanced Defense Serum

69% match

with the ingredients and function of GoodnDoc Hydra B5 Serum

81% Attribute Match
56% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #4

Hyaloo White Truffle Serum Spray

68% match

with the ingredients and function of Cetaphil Advanced Defense Serum

86% Attribute Match
50% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #5

Mizon Hyalugen Le Lift Serum

68% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
47% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

This dupe is $2.16 more expensive than the original product.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #6

KoeRX Gorjes Magnificent Ace Serum

68% match

with the ingredients and function of Cetaphil Advanced Defense Serum

83% Attribute Match
55% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 9 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #7

Avène Hydrance Boost Concentrated Hydrating Serum

67% match

with the ingredients and function of Cetaphil Advanced Defense Serum

88% Attribute Match
49% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $11.65 more expensive than the original product.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #8

PURITO Pure Vitamin C Serum

67% match

with the ingredients and function of Cetaphil Advanced Defense Serum

71% Attribute Match
55% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

This dupe is $9.04 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #9

Dermatica Daily Hydration 5HA+Cica Serum

67% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #10

Glad I Met You Anti-Acne & Oil Control Face Serum

67% match

with the ingredients and function of Cetaphil Advanced Defense Serum

78% Attribute Match
53% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #11

Nevada Vitamin E + Alpha Arbutin Serum

67% match

with the ingredients and function of Cetaphil Advanced Defense Serum

86% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #5

Cetaphil Advanced Defense Serum

67% match

with the ingredients and function of Merit Beauty Great Skin Instant Glow Serum

100% Attribute Match
46% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $0.84 more expensive than the original product.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #12

Ruruberry NPAA Serum

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
44% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #13

feelxo: Glacier 5D Hyaluronic Serum

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

80% Attribute Match
52% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #14

Tia’m Pore Minimizing 21 Serum

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

75% Attribute Match
52% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

This dupe is $7.94 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #15

HALE Even Tone Potion

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
50% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Don't miss the latest dupes
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Dupe #16

Cute Press Calming Cica Booster Serum

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

100% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #17

Seonglow 15+ Niacinamide Vegan Serum

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

71% Attribute Match
56% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 10 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $0.86 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #18

Reyal Performance Serum [002]

66% match

with the ingredients and function of Cetaphil Advanced Defense Serum

86% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #19

Oh K! Illuminating Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #20

Colibri Skincare Niacinamide Booster

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #21

Nano Recipe Niacinamide 20% Concentrate Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

83% Attribute Match
49% Ingredient Match

Dupe Explained

These products are both serums that contain niacinamide. They've got a total of 4 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $3.92 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #22

Skindoze Glow Get It! Brightening Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

75% Attribute Match
50% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #23

Mary & May Hyaluronics Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

68% Attribute Match
55% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $7.51 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #24

Rael Miracle Clear Microcrystal Activated PM Serum 2000

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $3.15 more expensive than the original product.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #25

Dermaid 5% Niacinamide Concentrated Whitening Boost Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #26

Julioly Green Fig Smoothing Filter Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #27

Physician's Formula Skin Booster Vitamin Shot Hydrating

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
47% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Price Comparison

This dupe is $9.44 less expensive than the original product. Nice find!

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #28

Soul Apothecary Alpha Arbutin Plus Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

100% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #29

Jorgobé Niacinamide Serum

65% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
46% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #30

iUNIK Rose Galactomyces Synergy Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

81% Attribute Match
47% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #34

Cetaphil Advanced Defense Serum

64% match

with the ingredients and function of Avène Retrinal Advanced Correcting Serum

83% Attribute Match
45% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

This dupe is $58.16 less expensive than the original product. Nice find!

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Dupe #31

Cute Press 1 Week Brightening Booster Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

94% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $12.91 more expensive than the original product.

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Dupe #32

Soul Apothecary Radiance Boost Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

100% Attribute Match
39% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $11.85 less expensive than the original product. Nice find!

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Dupe #33

Tia’m Vita B3 Source

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

92% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $9.44 less expensive than the original product. Nice find!

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Dupe #34

Boots Ingredients Hyaluronic Acid Serum 2%

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

70% Attribute Match
52% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for dry skin, brightening skin, sensitive skin and scar healing.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #35

Dr.G 3X Panthenol Hyaluronic Acid Booster Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

88% Attribute Match
42% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

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Dupe #36

Barle Soothing Barrier Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

83% Attribute Match
46% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #37

Cledbel Collagen Niacinamide Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

83% Attribute Match
49% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $5.16 more expensive than the original product.

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Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #38

Apoliva Advanced Niacinamid Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #39

Forganica Skincare Pore Tightening Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
44% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #40

Believe Beauty Hyaluronic Acid Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

79% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #41

Clay And Glow Niacinamide Treatment Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

78% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #42

IVY AÏA Blossom Face Serum With Hyaluronic Acid

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

71% Attribute Match
51% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid. They've got a total of 7 ingredients in common.

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #43

Avène Hyaluron Activ B3 Concentrated Plumping Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

90% Attribute Match
44% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid and niacinamide. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

This dupe is $13.76 more expensive than the original product.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #44

Fuzed The Barrier Repair Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

86% Attribute Match
45% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 6 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #45

Bioderma Hydrabio Hyalu+ Serum

64% match

with the ingredients and function of Cetaphil Advanced Defense Serum

75% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both serums that contain hyaluronic acid, niacinamide and Vitamin E. They've got a total of 9 ingredients in common.

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates.

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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