Benadryl Dupes

Last updated on April 08, 2025

Welcome to our complete breakdown of the top 21 Benadryl dupes and alternatives that we've found.

If you're searching for dupes of a specific Benadryl product, you can use our Dupe Finder to search for them!

We use hundreds of science-backed factors to find you the best dupes.
Learn more about our dupe methodology

Our Roundup

Here's a quick roundup of our findings. Continue reading for the full breakdown!

Equate Extra Strength Anti-Itch Cream
Most Similar Ingredients

Equate's Extra Strength Anti-Itch Cream is the dupe with the most similar ingredients. Our matching methodology puts it at an 83% ingredient match to Benadryl's Extra Strength Anti-Itch Topical Analgesic Cream!

Equate Extra Strength Anti-Itch Cream
Most Liked

Of all of the dupes for this product, Equate's Extra Strength Anti-Itch Cream is the most liked by our community. Our matching algorithm puts it at an 88% overall match with Benadryl's Extra Strength Anti-Itch Topical Analgesic Cream!

Dupe #1

Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

88% match

with the ingredients and function of Equate Extra Strength Anti-Itch Cream

88% Attribute Match
83% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 8 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

87% match

with the ingredients and function of up&up Extra Strength Itch Relief Cream

75% Attribute Match
86% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 9 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates. They both contain parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Cooling Spray

85% match

with the ingredients and function of Equate Extra Strength Anti-Itch Continuous Spray

78% Attribute Match
80% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 6 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates. They both contain harsh alcohols.

They're both likely to be good for dry skin and brightening skin.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Equate Extra Strength Anti-Itch Continuous Spray

85% match

with the ingredients and function of Benadryl Extra Strength Itch Relief Stick

78% Attribute Match
80% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 6 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates. They both contain harsh alcohols.

They're both likely to be good for dry skin and brightening skin.

Both products are also reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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Dupe #3

R&R Lotion I.C. Ivy Relief Stick

76% match

with the ingredients and function of Benadryl Extra Strength Itch Relief Stick

80% Attribute Match
69% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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Dupe #3

R&R Lotion I.C. Ivy Relief Stick

76% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Cooling Spray

80% Attribute Match
69% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Cooling Spray

76% match

with the ingredients and function of R&R Lotion I.C. Industrial Itch & Pain Relief Stick

80% Attribute Match
69% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

R&R Lotion I.C. Industrial Itch & Pain Relief Stick

76% match

with the ingredients and function of Benadryl Extra Strength Itch Relief Stick

80% Attribute Match
69% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

Both products are also fungal acne (malassezia) safe and reef safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Equate Calaspray Itch Relief Clear Skin Protectant

66% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

78% Attribute Match
47% Ingredient Match

Dupe Explained

These products are both body treatments that contain AHA. They've got a total of 7 ingredients in common.

They both do not contain any oils, silicones or sulfates. They both contain harsh alcohols and common allergens.

They're both likely to be good for dry skin, brightening skin, reducing pores, scar healing and better texture.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

64% match

with the ingredients and function of up&up Extra Strength Itch Relief Cream

67% Attribute Match
48% Ingredient Match

Dupe Explained

These products are both body treatments that contain AHA. They've got a total of 7 ingredients in common.

They both do not contain any fragrances, oils, silicones or sulfates. They both contain parabens.

They're both likely to be good for brightening skin, reducing pores, scar healing and better texture.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

62% match

with the ingredients and function of CVS Health Hydrocortisone Cream Regular Strength 0.5%

73% Attribute Match
43% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates. They both contain parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #2

up&up Pain Relieving Cleansing Spray

60% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

71% Attribute Match
38% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 5 ingredients in common.

They both do not contain any harsh alcohols, common allergens, oils, silicones or sulfates. They both contain parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Cooling Spray

59% match

with the ingredients and function of up&up Povidone-Iodine Solution

63% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for dry skin and brightening skin.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

59% match

with the ingredients and function of R&R Lotion I.C. Ivy Relief Stick

63% Attribute Match
40% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

up&up Povidone-Iodine Solution

59% match

with the ingredients and function of Benadryl Extra Strength Itch Relief Stick

63% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any common allergens, fragrances, oils, parabens, silicones or sulfates.

They're both likely to be good for dry skin and brightening skin.

Both products are also fungal acne (malassezia) safe and reef safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

Benadryl Extra Strength Anti-Itch Topical Analgesic Cream

59% match

with the ingredients and function of R&R Lotion I.C. Industrial Itch & Pain Relief Stick

63% Attribute Match
40% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Don't miss the latest dupes
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Dupe #3

Icy Hot Pro Pain Reliever Dry Spray

57% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

67% Attribute Match
38% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 4 ingredients in common.

They both do not contain any fragrances, oils, silicones or sulfates. They both contain harsh alcohols and common allergens.

They're both likely to be good for dry skin and brightening skin.

Both products are also fungal acne (malassezia) safe.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #4

Tiger Balm Arthritis Rub Pain Relieving Cream

56% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

54% Attribute Match
41% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 6 ingredients in common.

They both do not contain any silicones. They both contain common allergens and parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #8

Equate Extra Strength Anti-Itch Cream

55% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

56% Attribute Match
37% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 5 ingredients in common.

They both do not contain any fragrances, oils, silicones or sulfates. They both contain parabens.

Price Comparison

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #1

R&R Lotion I.C. Industrial Itch & Pain Relief Stick

52% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

51% Attribute Match
35% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any fragrances, oils, silicones or sulfates.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

Dupe #14

R&R Lotion I.C. Ivy Relief Stick

52% match

with the ingredients and function of Benadryl Extra Strength Anti-Itch Topical Analgesic Gel

51% Attribute Match
35% Ingredient Match

Dupe Explained

These products are both body treatments that contain. They've got a total of 3 ingredients in common.

They both do not contain any fragrances, oils, silicones or sulfates.

Both products are also fungal acne (malassezia) safe.

Learn more about this dupe

Looking for a full breakdown of the similarities and differences between these two products?

Check out our full comparison of these two products for all the details!

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