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Curology Custom RX Serum (Tretinoin 0.035%, Azelaic Acid 5%, Niacinamide 4%) Ingredients Explained

Prescription
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Updated on January 31, 2024 Submitted by stopthislady

Overview

What it is

Prescription with 13 ingredients that contains niacinamide, retinoid and Vitamin E

Cool Features

It is vegan, cruelty-free, and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

Fun facts

Curology is from United States. This product is used in 3 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

Prescription with 13 ingredients that contains niacinamide, retinoid and Vitamin E

Quick info

You should know

Notable Ingredients

Benefits

Concerns

Ingredients 13

Tretinoin
Retinoid  •  3 Benefits  •  2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Azelaic Acid Buffering, Masking
5 Benefits

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

Niacinamide Smoothing
Niacinamide  •  6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Aloe Barbadensis Leaf Juice Skin Conditioning
2 Benefits

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

C13-14 Isoparaffin Emollient, Solvent
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
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Vitamin E  •  Antioxidant  •  Helps brighten skin

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Triethylene Glycol Masking, Perfuming
Fragrance

Triethylene Glycol is a fragrance.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
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May worsen Eczema

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Very Disliked Full details ->

Ingredient Ratings

Based on the number of likes and dislikes each ingredient has received.

6
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5
1
liked
mixed
disliked
not rated

Ingredients Explained

This product contains 13 ingredients. Click on any ingredient to learn more about it
Loved

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All forms of OTC retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
Buffering, Masking
Loved

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.

Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.

One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people. It is also non-comedogenic, meaning that it will not clog pores.

Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.

Learn more about Azelaic Acid
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning
Liked

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.

Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.

It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

Learn more about Aloe Barbadensis Leaf Juice
Emollient, Solvent
Very Disliked

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.

C13-14 Isoparaffin may not be fungal-acne safe.

Learn more about C13-14 Isoparaffin
Masking, Skin Conditioning
Mixed

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying
Disliked

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Laureth-7 is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Disliked

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Learn more about Polyacrylamide
Antioxidant, Skin Conditioning
Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Masking, Perfuming

Triethylene Glycol is a fragrance.

Humectant, Skin Conditioning, Solvent
Very Disliked

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may deliver a rash when using this ingredient.

Learn more about Propylene Glycol

When to use

How this product is used by our community

3 Routines
0% use in am
100% use in pm
100% use every day

Directions

Apply your serum before bed, leave it on while you sleep, and let it do its work overnight.

Apply your serum before bed, leave it on while you sleep, and let it do its work overnight.

Verified by SkinSort

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The data we've presented on this page has been verified by a member of the SkinSort Team.

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